Results 141 to 150 of about 165,402 (265)

A Personalized Therapeutic Approach for Liver Cancers Expressing the African-Centric P47S Variant of TP53. [PDF]

open access: yesMol Cancer Res
Foster M   +7 more
europepmc   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

open access: yesVIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang   +7 more
wiley   +1 more source

Adipose Triglyceride Lipase and Gpr40 Contribute to the Anti-Contractile Effect of Perivascular Adipose Tissue. [PDF]

open access: yesMicrocirculation
Hyatt M   +9 more
europepmc   +1 more source

An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda   +6 more
wiley   +1 more source

Sodium Diclofenac‐Loaded Drug Delivery Microspheres: Impact on Calcium Hydroxide Paste Properties and Biological Response

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT This study evaluated whether the incorporation of sodium diclofenac‐loaded microspheres into a calcium hydroxide paste enhances antibiofilm activity while maintaining physicochemical properties and biocompatibility. Calcium hydroxide paste, calcium hydroxide combined with sodium diclofenac, and calcium hydroxide containing sodium diclofenac ...
João Vitor Oliveira de Amorim   +6 more
wiley   +1 more source

Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats. [PDF]

open access: yesJ Physiol
Felippe ISA   +11 more
europepmc   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

open access: yesAndrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz   +12 more
wiley   +1 more source

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