Results 161 to 170 of about 165,402 (265)

Subregion‐specific perineuronal net remodelling in the dorsal hippocampus drives vulnerability and resilience to chronic stress: The role of venlafaxine treatment

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio   +11 more
wiley   +1 more source

Neuroimmune alterations and nociceptive behavior in oral carcinogenesis in rats

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract Oral cancer pain is a frequent and debilitating symptom associated with tumor progression. Although neuronal mechanisms have been extensively studied, the role of immune and glial cells in the trigeminal nociceptive pathway remains poorly understood.
Joana Maria dos Santos Alves   +7 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

open access: yesThe FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz   +13 more
wiley   +1 more source

Alogliptin Delays the Healing of Traumatic Oral Ulcers in the Buccal Mucosa of Wistar Rats. [PDF]

open access: yesFundam Clin Pharmacol
de Queiroz Rodrigues MI   +6 more
europepmc   +1 more source

CD68 and F4/80 Markers Demonstrate Inflammatory Synergism Between Apical Periodontitis and Liver Fibrosis in Wistar Rats

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti   +9 more
wiley   +1 more source

SynapTrack: An automated tool for synapse quantification

open access: yesJournal of Microscopy, EarlyView.
Abstract Reliable synapse quantification remains challenging, particularly in high‐throughput fluorescence imaging workflows. Here we present SynapTrack, a fully automated FIJI/ImageJ‐based tool for quantifying synapses in cultured neurons and brain tissue sections with minimal user intervention.
Carlos Gallego‐García   +2 more
wiley   +1 more source

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