Results 151 to 160 of about 165,402 (265)

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Acute (14-Day) and Subchronic (90-Day) Toxicity Evaluation of the Dried Fruit Spice <i>Xylopia aethiopica</i> (Dunal) A. Rich. (Annonaceae) in Male and Female Wistar Rats. [PDF]

J Toxicol
Nguedia MY, Nkuimi OBK, Mafogang B, Ngatanko HHA, Njamen D, Zingue S.   +5 more
europepmc   +1 more source

Role of ANO1‐Expressing PDGFRα+ Smooth Muscle Cells in Generating Spontaneous Phasic Contractions of the Rodent Epididymis

Andrology, EarlyView.
ABSTRACT Background Spontaneous phasic contractions (SPCs) in the epididymal duct play an important role in transport and maturation of sperm. In proximal cauda of the rat epididymis, platelet‐derived growth factor receptor α (PDGFRα)‐positive smooth muscle cells (SMCs) generate ANO1 Ca2+‐activated chloride channels (CaCCs)‐dependent spontaneous ...
Wataru Kudo, Hiromichi Takano, Toshiya Izuchi, Retsu Mitsui, Kyoko Miwa‐Nishimura, Hikaru Hashitani   +5 more
wiley   +1 more source

RETRACTED: Osman et al. Lipolytic Postbiotic from <i>Lactobacillus paracasei</i> Manages Metabolic Syndrome in Albino Wistar Rats. <i>Molecules</i> 2021, <i>26</i>, 472. [PDF]

Molecules
Osman A, El-Gazzar N, Almanaa TN, El-Hadary A, Sitohy M.   +4 more
europepmc   +1 more source

Reactivity of Wistar rats to dextran

Journal of Pharmacy and Pharmacology, 1965
S I, ANKIER, G B, WEST, J M, HARRIS, D K, LUSCOMBE   +3 more
openaire   +2 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

454 Checkpoint modification of early T cell activation provides enhanced anti-tumor activity and survival benefits in a fast-growing preclinical tumor challenge model

Journal for ImmunoTherapy of Cancer, 2023
Sue L Currie, Mohsen Mohammadi, Xiang Y Zhou, Zhi Xiang, Wynetta Giles-Davis, Andrew Luber, Hildegund CJ Ertl   +6 more
doaj   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Differences on the Natural Course of Chronic Kidney Disease Progression, Induced by 5/6 Renal Ablation Model in Three Different Rat Stains: Wistar, Lewis, and Fischer 344. [PDF]

Life (Basel)
Jesus S, Noda PS, Francini ALR, Teles Filho F, Veras MM, Nunes ACF, Noronha IL, Fanelli C.   +7 more
europepmc   +1 more source

Serotonin engages divergent 5‐HT receptor pathways for cell type‐resolved modulation of prefrontal layer 5 microcircuits

British Journal of Pharmacology, EarlyView.
Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama, Guanxiao Qi, Gabriele Radnikow, Danqing Yang, Dirk Feldmeyer   +4 more
wiley   +1 more source