Results 71 to 80 of about 392,814 (345)

The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats

BioMed Research International, 2014
Background. Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. Aims.
Norshalizah Mamikutty, Z. C. Thent, S. R. Sapri, N. N. Sahruddin, Mohd Rafizul Mohd Yusof, F. Haji Suhaimi   +5 more
semanticscholar   +1 more source

Aortic depressor nerve differences between Wistar and Wistar‐Kyoto rats

The FASEB Journal, 2012
Previous reports from our laboratory [1, 2, 3] showed differences on the morphology of the aortic depressor nerve (ADN) between normotensive Wistar‐Kyoto (WKY) and spontaneously hypertensive rats (SHR). The aim of the present study was to investigate if there are morphological and morphometric differences on the AND of two different normotensive rats ...
Milena Menezes de Amorim, Helio Cesar Salgado, Letícia Oliveira Neri da Silva, Valéria Paula Sassoli Fazan, Vânia Alice de Aguiar Mendes   +4 more
openaire   +2 more sources

Wistar Diabetic Fatty Rat [PDF]

ILAR Journal, 1990
Wistar diabetic fatty (WDF/Ta-/a) rats were developed by Ikeda et al. (1981) to provide a rat model of non-insulindependent diabetes mellitus (NIDDM). Human NIDDM is typically characterized by adult onset and varying degrees of obesity, hyperglycemia, hyperinsulinemia, insulin resistance, glucose intolerance, and peripheral neuropathy.
David B. West, Richard G. Peterson, M. R. C. Greenwood, Ruth Kava   +3 more
openaire   +2 more sources

Highly Efficient Classification of Time‐Series Based on Resistive Switching Cluster‐Assembled Materials

Advanced Intelligent Systems, EarlyView.
Cluster‐assembled nanocomposite devices are employed for the classification of neuronal traces, without any preprocessing of the input time‐series or prior training of the nonlinear devices. The classification method relies on the statistical analysis of the device's output time‐series, achieving higher classification accuracy compared to more energy ...
Filippo Profumo, Francesca Borghi, Tommaso Angì, Marta Maschietto, Stefano Vassanelli, Paolo Milani   +5 more
wiley   +1 more source

Learned helplessness and social avoidance in the Wistar-Kyoto rat

Frontiers in Behavioral Neuroscience, 2014
The Wistar-Kyoto (WKY) rat is an established depression model characterized by elevated anxiety- and depression-like behavior across a variety of tests. Here we further characterized specific behavioral and functional domains relevant to depression that ...
H. Nam, S. Clinton, N. Jackson, I. Kerman   +3 more
semanticscholar   +1 more source

Animal models of cisplatin‐induced neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li, Mingzhu Li, Shengbo Jin, Jun Yu, Hongzhe Wei, Wenping Wang, Siyao Ma, Yuxin Jiang, Qian Liu, Huini Yao   +9 more
wiley   +1 more source

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

PLoS ONE, 2011
The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, stress resistance and longevity. Apart from its role as an important redox carrier, NAD+ also serves as the sole substrate for NAD-dependent enzymes ...
N. Braidy, G. Guillemin, Hussein Mansour, T. Chan-Ling, A. Poljak, R. Grant   +5 more
semanticscholar   +1 more source

Ultrastructural investigation of the aortic depressor nerve in Wistar and Wistar‐Kyoto rats

The FASEB Journal, 2012
Ultrastructural study of the aortic depressor nerve (ADN) [1] showed differences on the morphology and morphometry between normotensive Wistar‐Kyoto (WKY) and spontaneously hypertensive rats (SHR), particularly in the number of unmyelinated fibers. The aim of the present study was to investigate if there are ultrastructural differences on the AND of ...
Vânia Alice de Aguiar Mendes, Valéria Paula Sassoli Fazan, Helio Cesar Salgado, Milena Menezes de Amorim, Letícia Oliveira Neri da Silva   +4 more
openaire   +2 more sources

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Differential Sensitivity to Morphine in Spontaneously Hypertensive and Normotensive Wistar-Kyoto and Wistar Rats

Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987
In spontaneously hypertensive rats (SHR) a diminished responsiveness for nociceptive stimuli is present, which might be associated with alterations in endogenous opioid peptide and receptor systems. In SHR, normotensive Wistar-Kyoto controls (WKY) and in Wistar rats the effects of acute morphine administration on pain sensitivity and body temperature ...
Frans P. Nijkamp, J. M. A. Sitsen, W. De Jong   +2 more
openaire   +3 more sources