Results 81 to 90 of about 299,160 (302)

Conformational landscape of HIV-1 Env from closed to fully open

Nature Communications
The molecular mechanism of HIV-1 entry into host cells is governed by dynamic conformational changes to its envelope glycoprotein (Env), which are triggered by the engagement of the host receptor CD4 and coreceptors.
Jiayan Cui, Zi Jie Lin, Sukanya Ghosh, Jianqiu Du, Roopak Sadeesh, David B. Weiner, Jesper Pallesen   +6 more
doaj   +1 more source

Trichosomoides crassicauda Infection in Wistar Rats

, 1999
Natural infection of locally bred Wistar rats with Trichosomoides cra.fsicauda produced hypertrophic changes in the transitional epithelium of the urinary bladder and renal pelvis and suppurative pneumonia.
Haroun, E.M., Magzoub, M., Sulman, A., Al-Humaid, Fatima, Omer, O.H, Mahmoud, O.M., Al-Qarawi, A.A.   +6 more
core  

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer

mBio
Epstein–Barr virus-associated gastric cancer (EBVaGC) accounts for ~9% to 10% of gastric cancers worldwide and is defined by a distinctive molecular profile, including extreme hypermethylation of the DNA.
Sarah Preston-Alp, Yin Wang, Matteo Bergonzoni, Andrew Kossenkov, Samantha S. Soldan, Lisa Beatrice Caruso, Davide Maestri, Paul M. Lieberman, Benjamin E. Gewurz, Italo Tempera   +9 more
doaj   +1 more source

Noninvasive or minimally invasive neuromodulation in animal models of acute ischemic stroke: A systematic review and meta-analysis. [PDF]

Neuroprotection
This systematic review and meta‐analysis assessed the cytoprotective effects of neuromodulation in preclinical models of ischemic stroke. Pooled analyses showed that neuromodulation significantly reduced infarct volume and improved neurological outcomes.
Salles IC, Pellegrino MP, Kroth JB, Dos Santos CL, Tristao LS, Shinosaki JSM, Bernardo WM, Conforto AB.   +7 more
europepmc   +2 more sources

O uso da tela de poliamida na peritonite experimental em ratos wistar [PDF]

, 2004
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Muller, Cyro Riggenbach
core  

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains [PDF]

, 2009
Background Cognitive function might be affected by the subjects' emotional reactivity. We assessed whether behavior in different tests of emotional reactivity is correlated with performance in aversively motivated learning tasks, using four strains of ...
Korte S Mechiel, Schuurman Teun, Korte, S.M., Sub BasicPharmacology&Psychopharmacology, Staay, F.J., van der, van Reenen, C.G., van der Staay F Josef, van der Staay, F.J., Cornelis G van Reenen, Schuurman, T., Reenen, C.G., van, Dep Gezondheidszorg Landbouwhuisdieren, F Josef van der Staay, van Reenen Cornelis G, Emotion and Cognition, S Mechiel Korte, Dierexperimenteel, Teun Schuurman   +17 more
core   +2 more sources

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source