Results 71 to 80 of about 121,158 (266)

True hermaphroditism in a wistar rat

Brazilian Journal of Veterinary Pathology, 2009
A rare case of true hermaphroditism was observed in a 9-week-old presumed female Wistar rat. This rat did not reveal any untoward clinical signs, food consumption, body weight gain and changes in haemato-biochemical parameters.
R. Madheswaran, V. V. Pande, P. Kalaiselvan, K. Y. Mathur, P. D. Shelar, J. J. Bhelonde, Venkatesha Udupa, V. M. Shingatgeri   +7 more
doaj   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Histological Effects of Aqueous Extract of Carica papaya Seed on the Renal Tissue in Adult Wistar Rats

Sokoto Journal of Medical Laboratory Science, 2019
Attention has been given to some tropical fruit that are of medicinal importance among which is Carica papaya. Papaya is the fruit of the plant carica papaya and the sole specie in the genus carica of the caricacae family.
Ekundina, V.O.* , Ebeye, O.A. and Odigie, B.O.
doaj  

Degeneration of Rat Retina is Paralleled by an Imbalance of the Redox Mechanism of Pteridines

Pteridines, 1996
The RCS rat suffers from a genetic degeneration of retinal cell We have examined the pattern of oxidized and reduced monapterin and biopterin in retinas from RCS retinas and controls.
Cremer-Bartels Gertrud
doaj   +1 more source

Decreased reward sensitivity in rats from the Fischer344 strain compared to Wistar rats is paralleled by differences in endocannabinoid signaling.

PLoS ONE, 2012
BackgroundThe aim of the present study was to examine if differences in the endocannabinoid (ECB) system might be linked to strain specific variations in reward-related behavior in Fischer344 (Fischer) and Wistar rats.Methodology/principal findingsTwo ...
Theresa Brand, Rainer Spanagel, Miriam Schneider   +2 more
doaj   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Corneal Mineralization in Wistar Hannover Rats

Journal of Toxicologic Pathology, 2013
We have recently started using Wistar Hannover rats in Japan and are now collecting background data. We have been frequently observing corneal mineralization in Wistar Hannover rats of both the RccHan(TM):WIST and Crl:WI (Han) strains. In this study, details of corneal mineralization in Wistar Hannover rats were histopathologically and ...
HASHIMOTO, Satomi, DOI, Takuya, WAKO, Yumi, SATO, Junko, WADA, Sou, TSUCHITANI, Minoru   +5 more
openaire   +3 more sources

Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats

Epilepsia, EarlyView.
Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire, Elise Collard, Abigail Niyibizi, Natasha N. Kumar, Enrique Germany Morrison, Javier Chavez Cerda, Ayse S. Dereli, Riem El Tahry   +7 more
wiley   +1 more source

The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats

BMC Cardiovascular Disorders, 2003
Background Elevated plant sterol accumulation has been reported in the spontaneously hypertensive rat (SHR), the stroke-prone spontaneously hypertensive rat (SHRSP) and the Wistar-Kyoto (WKY) rat.
Klein Richard, Sato Masao, Egashira Nami, Ikeda Ikuo, Helou Khalil, Lu Kangmo, Lee Mi-Hye, Klett Eric, Pandit Bhaswati, Yu Hongwei, Batta Ashok, Salen Gerald, Patel Shailendra B   +12 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source