Results 81 to 90 of about 121,158 (266)

A Rat Model for Cyclosporine A Nephrotoxicity: A Study on Wistar Strain Rats

Turkish Journal of Nephrology, 2019
Nephrotoxicity is a side effect of cyclosporine A (CsA), which is used after transplantation. In CsA-treated patients, factors other than the drug may also have renal and cardiovascular effects.
Cevat YAZICI, Kader KÖSE, Süleyman GÖKALP, Özlem CANÖZ   +3 more
doaj   +2 more sources

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Evaluating the Effects of Moringa Oleifera Leaf Extract on Testosterone Level of Male Wistar Rats Exposed to Petrol, Diesel and Kerosene

Sokoto Journal of Medical Laboratory Science
Testes are primary organ of reproduction as they are responsible for the production and release of testosterone. Testosterone is the major androgenic steroid hormone produced primarily in the Leydig cells, it has both intratesticular and peripheral ...
Bashir Saidu', Ashiru Dahiru', Aliyu Jibril’, Ahmad Musa Dunfawa', Nafisat Abdulazeez' and Muawiyyah Muhammad Mahuta’
doaj  

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

The Effect of Cabergoline on the Clinical and Immunological Aspects of Rheumatoid Arthritis Induced in Wistar Rats

Armaghane Danesh Bimonthly Journal, 2019
Background & aim: The anti-inflammatory effects of cabergoline have been documented in various studies. The purpose of the present study was to evaluate the effects of cabergoline administration (as a potent D2 agonist) on clinical aspects and immune ...
E Shaftaloud, SM Abtahi Froushani, N Delirezh   +2 more
doaj  

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Nutritional, Functional, and Anti‐Hypercholesterolemic Properties of Sourdough Breads From Unripe Plantain, Tiger Nut, and Fenugreek Flours

Food Chemistry International, EarlyView.
Composite sourdough breads were developed from blends of unripe plantain, tiger nut, and fenugreek flours. Optimized formulations improved pasting stability and enhanced texture, producing softer more elastic crumbs. The enriched breads contained higher dietary fiber and bioactive compounds, and significantly reduced serum cholesterol markers ...
Mary T. Ademosun, Olufunmilayo S. Omoba, Ganiyu Oboh, Adedamola I. Akinyede, Rukayat O. Awolola   +4 more
wiley   +1 more source

Dopamine depletion in wistar rats with epilepsy

Brazilian Journal of Biology
Abstract The dopamine content in cerebral structures has been related to neuronal excitability and several approaches have been used to study this phenomenon during seizure vulnerability period. In the present work, we describe the effects of dopamine depletion after the administration of 6-hidroxidopamine (6-OHDA) into the substantia nigra pars ...
E. M. Trindade-Filho, J. Dal Pai, D. N. de Castro, A. T. M. da Silva, A. F. Costa, J. S. S. Vieira, S. D. B. dos Santos, V. B. Félix, S. A. B. F. Leão, L. I. Zambrano, A. J. M. Saldanha-Filho, E. G. A. Carvalho, J. B. N. Cavalcante, G. B. Quintella, A. T. S. Lino, M. V. Costa, J. A. Lima, M. M. A. Tavares, M. R. de Melo, K. C. Mousinho, C. L. C. L. De Biase, M. L. Leite, P. J. M. S. Costa, E. L. Becker, I. M. F. B. Moura, J. C. da Silva   +25 more
openaire   +5 more sources

Donkwa Enriched With Goron‐Tula (Azanza garckeana) Modulates Sexual Behavior and Activity of Enzymes Linked With Erectile Dysfunction in High‐Fat Diets/ Streptozotocin‐Induced (STZ/HFD) Diabetic Rats

Food Chemistry International, EarlyView.
(A) Mount number, (B) mount latency, (C) intromission number, and (D) intromission latency are the parameters of sexual behavior. Met = metformin. D100 = 100 Donkwa. D90G10 = 90% Donkwa + 10% Goron‐Tula. D85G15 = 85% Donkwa + 15% Goron‐Tula. D80G20 = 80% Donkwa + 20% Goron‐Tula. The mean ± standard error of the mean (SEM) expressed the results. *Values
O. T. Mamukuyomi, O. S. Ijarotimi, A. A. Badejo   +2 more
wiley   +1 more source