Results 251 to 260 of about 291,899 (358)
Differential Effects of Intrahippocampal Administration of Ceftriaxone on Morphine Dependence and Withdrawal Syndrome in Rats. [PDF]
Saeedi N+5 more
europepmc +1 more source
Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez+8 more
wiley +1 more source
Utilization of Proteomic Measures for Early Detection of Drug Benefits and Adverse Effects
Abstract Recognition of benefits and adverse effects of therapies in earlier clinical trial phases could improve the safety, efficiency, and cost of clinical trials. Using four clinical trials representing a diverse set of diseases and drug classes (EXSCEL: exenatide/GLP‐1 RA, SUGAR‐DM‐HF: empagliflozin/SGLT2i, PRADA: epirubicin/anthracycline, and ...
Jessica Chadwick+17 more
wiley +1 more source
Well-Child Visits and Immunization Encounters in South Carolina Medicaid: A 3-Year Retrospective Comparison Between Rural and Urban Children with a History of Neonatal Opioid Withdrawal Syndrome, 2006-2014. [PDF]
Tahsin F+7 more
europepmc +1 more source
Abstract Background Emotion and peer problems tend to increase in autistic young people during adolescence. However, the extent to which endogenous (e.g., pubertal maturation) and exogenous (e.g., school adjustment, bullying) factors contribute to trajectories of emotion and peer problems in autistic young people is unclear. Methods Using data from the
Erin O. Dawe‐Lane+3 more
wiley +1 more source
Androgen Receptor Signaling Inhibitor Withdrawal Syndrome After Castration-resistant Prostate Cancer. [PDF]
Hiroshi M.
europepmc +1 more source
This systematic review aimed to assess the current evidence on the efficacy and safety of Atomoxetine in common clinical symptoms of autism spectrum disorder (ASD) for children and adolescents. With limited studies available, there is a need for more high‐power studies for the use of Atomoxetine in children and adolescents with autism spectrum disorder.
Nihit Gupta+3 more
wiley +1 more source
Characterization of alcohol-related seizures in withdrawal syndrome. [PDF]
Kádár BK+4 more
europepmc +1 more source
Growing evidence suggests that difficulties reasoning about others' thoughts, feelings and desires (called ‘mentalizing’ or ‘theory of mind’) cut across many mental health and neurodevelopmental conditions but studies have yet to test this claim directly.
Rory T. Devine+2 more
wiley +1 more source