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Although psychiatric drug withdrawal syndromes have been recognized since the 1950s – recent studies confirm antidepressant withdrawal syndrome incidence upwards of 40% – medical information about how to safely go off the drugs has been lacking.
Adele Framer
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Concurrent opioid and alcohol withdrawal management [PDF]
Concurrent alcohol and opioid withdrawal syndrome is a common and challenging clinical scenario with little published evidence or guidance to inform pharmacotherapy strategies.
Michelle Colvard, PharmD, BCPP
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The effect of an incremental resistance training program on some apoptotic markers in the heart tissue of rats with morphine withdrawal syndrome [PDF]
Background and Aim: The use of different drugs in withdrawal syndrome usually has little effectiveness and causes the person to become dependent on new substances.
Maryam Sadegh joola +2 more
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Ethanol abuse is a major public issue globally and withdrawal of ethanol after chronic exposure contributes to the development of behavioural changes.
Lihui Du +3 more
core +1 more source
Baclofen: Therapeutic and Toxic Mechanisms of Action (Review)
Baclofen is a muscle relaxant, which is a beta-p-chlorophenyl derivative of an inhibitory neurotransmitter GABA. This drug may have serious side effects and cause life-threatening conditions which may recellular receptors to clarify the pathogenesis of ...
О. L. Romanova +2 more
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Neonatal Abstinence Syndrome: Prevention, Management and Outcomes: From Birth to Adulthood
Neonatal abstinence syndrome (NAS), or—when specifically focused on opioids—neonatal opioid withdrawal syndrome (NOWS) is a withdrawal syndrome in neonates after birth causally related to the in utero exposure to drugs of dependence, and the subsequent ...
Karel Allegaert, Ju-Lee Oei
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Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Nunez, Cristina +13 more
core +3 more sources
The pathophysiology of substance withdrawal is elucidated by a review of classic and cutting-edge research. The manifestation and evaluation of the associated withdrawal syndromes from ethanol, sedative-hypnotics, opioids, and baclofen, are compared. The general management of and pharmacotherapy for these patients are discussed.
R, Olmedo, R S, Hoffman
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Is There a Lithium Withdrawal Syndrome? [PDF]
Patients who discontinued lithium after a mean of 29 ± 21 months prophylaxis were compared with a similar group who were not taking the drug; all had only been in hospital once, and satisfied DSM-III criteria for mania. During the first three months following withdrawal of lithium, significantly more patients relapsed than in the control group; after ...
openaire +2 more sources
The convulsive syndrome in the structure of alcohol withdrawal syndrome with delirium
Introduction Withdrawal states with delirium, having convulsive syndrome in their structure, are one of the most severe emergency conditions in psychiatry. Objectives A total of 160 patients were examined with delirium alcohol withdrawal.
V. Kuzminov
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