Results 161 to 170 of about 3,705 (268)

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation [PDF]

, 2006
Tripti Gaur, Lillian Rich, Christopher J. Lengner, Sadiq Hussain, Brune Trevant, David C. Ayers, Janet L. Stein, Peter V.N. Bodine, Barry S. Komm, Gary S. Stein, Jane B. Lian   +10 more
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Tcl-2 encodes a novel protein that acts synergistically with Wnt signaling pathways in C. elegans

, 2003
Xiaojun Zhao, Hitoshi Sawa, M.A. Herman
openalex   +1 more source

Wnt Signaling and a Hox Protein Cooperatively Regulate PSA-3/Meis to Determine Daughter Cell Fate after Asymmetric Cell Division in C. elegans [PDF]

, 2006
Yukinobu Arata, Hiroko Kouike, Yanping Zhang, M.A. Herman, Hideyuki Okano, Hitoshi Sawa   +5 more
openalex   +1 more source

Microsphere Strategy to Generate Conformal Bone Organoid Units with Osteoimmunomodulation and Sustainable Oxygen Supply for Bone Regeneration

Advanced Science, EarlyView.
Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng, Hao Zhang, Yan Hu, Jilong Li, Jian Wang, Xiao Chen, Zhen Geng, Ke Xu, Yuxiao Lai, Jianhua Wang, Yingying Jing, Long Bai, Jiacan Su   +12 more
wiley   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

The Mitogen-Activated Protein Kinase Kinase Kinase Kinase GCKR Positively Regulates Canonical and Noncanonical Wnt Signaling in B Lymphocytes [PDF]

, 2006
Chong-Shan Shi, Ning‐Na Huang, Kathleen A. Harrison, Sang‐Bae Han, John H. Kehrl   +4 more
openalex   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Wnt 11 signaling induces proliferation and transformation of intestinal epithelial cells Iec6 and is mediated by a protein kinase C-dependent mechanism

, 2003
Lillian Ouko, Li H. Gu, Thomas R. Ziegler, Vincent W. Yang   +3 more
openalex   +1 more source

Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation [PDF]

, 2007
Amaya Miquelajáuregui, Tom Van de Putte, A. S. Polyakov, Anjana Nityanandam, Sridhar Boppana, Eve Seuntjens, Anton Karabinoš, Yujiro Higashi, Danny Huylebroeck, Victor Tarabykin   +9 more
openalex   +1 more source