Results 101 to 110 of about 1,026,340 (233)
Aldolase positively regulates of the canonical Wnt signaling pathway
The Wnt signaling pathway is an evolutionary conserved system, having pivotal roles during animal development. When over-activated, this signaling pathway is involved in cancer initiation and progression. The canonical Wnt pathway regulates the stability
M. Caspi+6 more
semanticscholar +1 more source
Establishment of the Dorso-ventral Axis in Xenopus Embryos Is Presaged by Early Asymmetries in β-Catenin That Are Modulated by the Wnt Signaling Pathway [PDF]
Carolyn A. Larabell+7 more
openalex +1 more source
Wnt signal transduction pathway and apoptosis: a review
The association between the wnt signaling pathway and apoptosis has become more firmly established in the recent scientific literature. Many reports indicate that the wnt signaling pathway regulates apoptosis through a variety of mechanisms. The activity
Pećina-Šlaus Nives
doaj +1 more source
The role of the Wnt signaling pathway in cancer stem cells: prospects for drug development
Cancer stem cells (CSCs), also known as tumor initiating cells are now considered to be the root cause of most if not all cancers, evading treatment and giving rise to disease relapse. They have become a central focus in new drug development. Prospective
Yong-Mi Kim, M. Kahn
semanticscholar +1 more source
Cyclic activation of the Wnt/β-catenin signaling pathway controls cell fusion-mediated somatic cell reprogramming. TCFs belong to a family of transcription factors that, in complex with β-catenin, bind and transcriptionally regulate Wnt target genes ...
Francesco Aulicino+4 more
doaj +1 more source
The Hedgehog (Hh) and Wnt/β-Catenin (Wnt) cascades are morphogen pathways whose pronounced influence on adult liver metabolism has been identified in recent years.
Aleithe, S.+20 more
core +1 more source
Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review.
Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt ...
L. Serman+3 more
semanticscholar +1 more source
Akt Participation in the Wnt Signaling Pathway through Dishevelled [PDF]
Shinya Fukumoto+11 more
openalex +1 more source
Mechanical Regulation of Wnt/β-catenin Signaling in Bone Cells [PDF]
poster abstractThe Wnt/β-catenin signaling pathway is an important regulatory pathway in development and maintenance of various tissues, including bone. Active Wnt interacts with the frizzled/LRP receptor activating dishevelled, which in turn inactivates
Gerard-O’Riley, R.+3 more
core
Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε [PDF]
Michiko Kishida+7 more
openalex +1 more source