Results 101 to 110 of about 1,026,340 (233)

Aldolase positively regulates of the canonical Wnt signaling pathway

open access: yesMolecular Cancer, 2014
The Wnt signaling pathway is an evolutionary conserved system, having pivotal roles during animal development. When over-activated, this signaling pathway is involved in cancer initiation and progression. The canonical Wnt pathway regulates the stability
M. Caspi   +6 more
semanticscholar   +1 more source

Establishment of the Dorso-ventral Axis in Xenopus Embryos Is Presaged by Early Asymmetries in β-Catenin That Are Modulated by the Wnt Signaling Pathway [PDF]

open access: bronze, 1997
Carolyn A. Larabell   +7 more
openalex   +1 more source

Wnt signal transduction pathway and apoptosis: a review

open access: yesCancer Cell International, 2010
The association between the wnt signaling pathway and apoptosis has become more firmly established in the recent scientific literature. Many reports indicate that the wnt signaling pathway regulates apoptosis through a variety of mechanisms. The activity
Pećina-Šlaus Nives
doaj   +1 more source

The role of the Wnt signaling pathway in cancer stem cells: prospects for drug development

open access: yesResearch and Reports in Biochemistry, 2014
Cancer stem cells (CSCs), also known as tumor initiating cells are now considered to be the root cause of most if not all cancers, evading treatment and giving rise to disease relapse. They have become a central focus in new drug development. Prospective
Yong-Mi Kim, M. Kahn
semanticscholar   +1 more source

Temporal Perturbation of the Wnt Signaling Pathway in the Control of Cell Reprogramming Is Modulated by TCF1

open access: yesStem Cell Reports, 2014
Cyclic activation of the Wnt/β-catenin signaling pathway controls cell fusion-mediated somatic cell reprogramming. TCFs belong to a family of transcription factors that, in complex with β-catenin, bind and transcriptionally regulate Wnt target genes ...
Francesco Aulicino   +4 more
doaj   +1 more source

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human

open access: yes, 2019
The Hedgehog (Hh) and Wnt/β-Catenin (Wnt) cascades are morphogen pathways whose pronounced influence on adult liver metabolism has been identified in recent years.
Aleithe, S.   +20 more
core   +1 more source

Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review.

open access: yesBosnian Journal of Basic Medical Sciences, 2014
Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt ...
L. Serman   +3 more
semanticscholar   +1 more source

Akt Participation in the Wnt Signaling Pathway through Dishevelled [PDF]

open access: hybrid, 2001
Shinya Fukumoto   +11 more
openalex   +1 more source

Mechanical Regulation of Wnt/β-catenin Signaling in Bone Cells [PDF]

open access: yes, 2010
poster abstractThe Wnt/β-catenin signaling pathway is an important regulatory pathway in development and maintenance of various tissues, including bone. Active Wnt interacts with the frizzled/LRP receptor activating dishevelled, which in turn inactivates
Gerard-O’Riley, R.   +3 more
core  

Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε [PDF]

open access: hybrid, 2001
Michiko Kishida   +7 more
openalex   +1 more source

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