Results 61 to 70 of about 22,945 (169)
This graphical abstract summarizes thiazole, thiazolidine‐2,4‐dione, and hybrid compounds investigated as antiviral candidates against dengue virus. Representative structures and reported potencies are presented in the context of DENV serotypes. Proposed molecular targets include NS2B–NS3 protease and NS5.
Pedro César de Souza +6 more
wiley +1 more source
Fold change is indicated in the columns based on mock-infected tissues. Red arrows indicate decreased gene expression and green arrows increased gene expression. Absence of arrows indicates no statistically significant change observed.
Terry L. Juelich (180664) +9 more
core +1 more source
Background West Nile virus (WNV) is a rapidly spreading mosquito-borne virus accounted for neuroinvasive diseases. An insight into WNV-host factors interaction is necessary for development of therapeutic approaches against WNV infection.
Yan-Gang Liu +4 more
doaj +1 more source
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod +29 more
wiley +1 more source
Structural analyses of WNV antigens secreted by HeLa3-WNV cells.
(A) WNV proteins released to the culture medium of HeLa3-WNV cells were purified by centrifugation through a 20% sucrose cushion and loaded onto a 20–60% linear sucrose gradient.
Estela Escribano-Romero (204519) +6 more
core +1 more source
SEROPREVALENCE OF WEST NILE VIRUS AND RELATED ORTHOFLAVIVIRUSES IN SOME ANIMAL SPECIES IN BULGARIA
Orthoflaviviruses are a notable threat to public health owing to their capacity to induce severe neuro-invasive disease. The present study aimed to synthesise seroprevalence data concerning West Nile virus (WNV) and Usutu virus (USUV) among selected ...
N. Rusenova, A. Rusenov
doaj +1 more source
A hamster-derived West Nile virus isolate induces persistent renal infection in mice. [PDF]
West Nile virus (WNV) can persist long term in the brain and kidney tissues of humans, non-human primates, and hamsters. In this study, mice were infected with WNV strain H8912, previously cultured from the urine of a persistently infected hamster, to ...
Vandana Saxena +10 more
doaj +1 more source
Abstract The Paris 2024 Olympic Games posed a unique challenge due to their scale, associated risks and the need for robust healthcare preparedness. This review outlines the forecasting and anticipatory measures taken by the Etablissement français du sang (EFS) to ensure a resilient blood supply chain throughout the event.
Jean‐Baptiste Thibert +9 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
WNV-immunostaining and histopathological immunostaining of the GI tract in WNV-infected hamsters.
Hamsters were injected s.c. with WNV or sham, and necropsied 9 days later. The intestine (duodenum, jejunum, ileum, colon) was sectioned for A) fluorescent immunohistochemical co-staining of WNV envelope and NSE and DAPI (nuclear), and B) WNV envelope ...
John D. Morrey (241718) +3 more
core +1 more source

