Results 41 to 50 of about 3,473 (203)

A possible new activator of PI3K‐Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction

open access: yesJournal of Cellular and Molecular Medicine, Volume 26, Issue 12, Page 3423-3445, June 2022., 2022
Abstract Obesity, which has unknown pathogenesis, can increase the frequency and seriousness of acute myocardial infarction (AMI). This study evaluated effect of Huayu Qutan Recipe (HQR) pretreatment on myocardial apoptosis induced by AMI by regulating mitochondrial function via PI3K/Akt/Bad pathway in rats with obesity.
He Tai   +10 more
wiley   +1 more source

Ninjinyoeito exerts an antidepressant‐like effect by enhancing the central noradrenergic system

open access: yesTraditional &Kampo Medicine, Volume 9, Issue 1, Page 25-31, April 2022., 2022
ABSTRACT Aim Ninjinyoeito (NYT) is a Kampo medicine prescribed for patients with decreased mental and physical energy. Clinical studies demonstrate that NYT ameliorates depressive symptoms in patients with various diseases. However, the underlying therapeutic mechanisms of action remain unclear.
Soichiro Tsutsumi   +9 more
wiley   +1 more source

Machine learning-based monosaccharide profiling for tissue-specific classification of Wolfiporia extensa samples

open access: yesCarbohydrate Polymers, 2023
Machine learning (ML) has been used for many clinical decision-making processes and diagnostic procedures in bioinformatics applications. We examined eight algorithms, including linear discriminant analysis (LDA), logistic regression (LR), k-nearest neighbor (KNN), random forest (RF), gradient boosting machine (GBM), support vector machine (SVM), Naïve
Shih-Yi, Hsiung   +7 more
openaire   +2 more sources

Genomic and Transcriptomic Insight of Giant Sclerotium Formation of Wood-Decay Fungi

open access: yesFrontiers in Microbiology, 2021
Many fungi form persistent and dormant sclerotia with compact hardened mycelia during unfavorable circumstances. While most of these sclerotia are small in size, Wolfiporia cocos, a wood-decay fungus, grows into giant sclerotia, which are mainly composed
Shuo Cao   +18 more
doaj   +1 more source

Characterization of Two Mitochondrial Genomes and Gene Expression Analysis Reveal Clues for Variations, Evolution, and Large-Sclerotium Formation in Medical Fungus Wolfiporia cocos

open access: yesFrontiers in Microbiology, 2020
Wolfiporia cocos, a precious mushroom with a long history as an edible food and Asian traditional medicine, remains unclear in the genetic mechanism underlying the formation of large sclerotia.
Mengting Chen   +7 more
doaj   +1 more source

A New Functional Classification of Glucuronoyl Esterases by Peptide Pattern Recognition [PDF]

open access: yes, 2017
Glucuronoyl esterases are a novel type of enzymes believed to catalyze the hydrolysis of ester linkages between lignin and glucuronoxylan in lignocellulosic biomass, linkages known as lignin carbohydrate complexes.
Busk, Peter Kamp   +4 more
core   +3 more sources

Attachment, Growth, and Detachment of Human Mesenchymal Stem Cells in a Chemically Defined Medium [PDF]

open access: yes, 2016
Citation: Denise Salzig, Jasmin Leber, Katharina Merkewitz, Michaela C. Lange, Natascha Köster, and Peter Czermak, “Attachment, Growth, and Detachment of Human Mesenchymal Stem Cells in a Chemically Defined Medium,” Stem Cells International, vol.
Czermak, Peter   +5 more
core   +3 more sources

The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties [PDF]

open access: yes, 2014
BACKGROUND: The sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden or Tiger milk mushroom (Polyporales, Basidiomycota) is a valuable folk medicine for indigenous peoples in Southeast Asia. Despite the increasing interest in this ethnobotanical mushroom,
Chon-Seng Tan   +6 more
core   +1 more source

A survey of genes encoding H2O2-producing GMC oxidoreductases in 10 Polyporales genomes [PDF]

open access: yes, 2015
15 p.-4 fig.-1 tab.The genomes of three representative Polyporales (Bjerkandera adusta, Phlebia brevispora and a member of the Ganoderma lucidum complex) recently were sequenced to expand our knowledge on the diversity and distribution of genes involved ...
Carro, Juan   +3 more
core   +1 more source

Bioinformatics Analysis, Expression Profiling, and Functional Characterization of Heat Shock Proteins in Wolfi-poria cocos

open access: yesBioengineering, 2023
Heat shock proteins (HSPs) play critical roles in regulating different mechanisms under high-temperature conditions. HSPs have been identified and well-studied in different plants.
Xin Hu   +9 more
doaj   +1 more source

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