Results 51 to 60 of about 1,298,739 (158)

Association of altered body composition with cardiac wasting in cancer with and without cardiotoxic therapy

British Journal of Pharmacology, EarlyView.
Created in BioRender: Scientific Figure and Illustration Software. Background and Purpose In advanced cancer, associations among changes in body composition, cardiac wasting and prior cardiotoxic anticancer therapy have not been investigated. Experimental Approach Using bioelectrical impedance analysis (BIA), body composition was measured in 206 ...
Sara Hadzibegovic, Jonathan L. Hella, Jan Porthun, Alessia Lena, Danara Krug, Iulia Baluta, Ursula Wilkenshoff, Amir A. Mahabadi, Matthias Totzeck, Tienush Rassaf, Stefan D. Anker, Wolfram Doehner, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Barry J. A. Laird, Richard J. E. Skipworth, John G. F. Cleland, Christian Oeing, Stephan von Haehling, Ulf Landmesser, Markus S. Anker   +21 more
wiley   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi, Laura Mundrucz, Máté Deák, Angéla Kecskés, Éva Borbély, Viktória Kormos, Balázs Gaszner, Orsolya Mihály, Balázs István Tóth, Joris Vriens, Thomas Voets, Erzsébet Kövesdi, Miklós Kecskés   +12 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

WFS1 mutation screening in a large series of Japanese hearing loss patients: Massively parallel DNA sequencing-based analysis. [PDF]

PLoS ONE, 2018
A heterozygous mutation in the Wolfram syndrome type 1 gene (WFS1) causes autosomal dominant nonsyndromic hereditary hearing loss, DFNA6/14/38, or Wolfram-like syndrome.
Masafumi Kobayashi, Maiko Miyagawa, Shin-Ya Nishio, Hideaki Moteki, Taro Fujikawa, Kenji Ohyama, Hirofumi Sakaguchi, Ikuyo Miyanohara, Akiko Sugaya, Yasushi Naito, Shin-Ya Morita, Yukihiko Kanda, Masahiro Takahashi, Kotaro Ishikawa, Yuki Nagano, Tetsuya Tono, Chie Oshikawa, Chiharu Kihara, Haruo Takahashi, Yoshihiro Noguchi, Shin-Ichi Usami   +20 more
doaj   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

Metagenomic detection and characterization of RNA viruses associated with Rhipicephalus linnaei (Audouin, 1826) ticks from the Amazon, Pará, Brazil

Medical and Veterinary Entomology, EarlyView.
Metagenomic analysis of Rhipicephalus linnaei from the Brazilian Amazon revealed the presence of RNA viruses belonging to the families Chuviridae, Phenuiviridae, Orthomyxoviridae and Rhabdoviridae. This study reports the first detection of Brown dog tick mivirus 1 and Brown dog tick phlebovirus 2 in Brazil, based on genomic characterization and ...
Lucas Henrique da Silva e Silva, Sandro Patroca da Silva, Fábio Silva da Silva, Leonardo Henrique Almeida Hernández, Daniel Damous Dias, Sâmia Luzia Sena da Silva, Lúcia Aline Moura Reis, Hanna Carolina Farias Reis, Bruna Laís Sena do Nascimento, Roberto Carlos Feitosa Brandão, Durval Bertram Rodrigues Vieira, Bruno Tardelli Diniz Nunes, Ana Cecília Ribeiro Cruz, Joaquim Pinto Nunes Neto   +13 more
wiley   +1 more source

Clinical Laboratory Innovations: Nanoscale Detection of Chloramphenicol Using Nanomaterial Biosensors

Analytical Science Advances, Volume 7, Issue 2, December 2026.
Nanosensor schematic functionalized with specific bioreceptors that produce electrochemical signals upon Chloramphenicol binding. Resulting voltammetric readouts (differential pulse, square‐wave, and cyclic voltammetry) are analyzed to identify and quantify Chloramphenicol.
Nava Moghadasian Niaki, Reza Kheradmand, Seyedeh Giso Akbarian, Elham Shaterian, Hamed Shaterian, Ahmad Mobed   +5 more
wiley   +1 more source

Wolfram syndrome 1 in the Italian population: genotype–phenotype correlations

, 2020
We studied 45 patients with Wolfram syndrome 1 (WS1) to describe their clinical history and to search for possible genotype-phenotype ...
Emanuela Mazzon, Mohamad Maghnie, Mazzon, E, D’Annunzio, G, Maghnie, Mohamad, Patti, G, Aloi, Concetta, Aloi, C, Concetta Aloi, Alessandro Salina, Chiara Di Bella, Fortunato Lombardo, Salzano, G, Caruso, R, Giuseppina Salzano, Rigoli, Luciana, Di Bella, Chiara, Lombardo, F., Giuseppa Patti, Salina, Alessandro, Salzano, Giuseppina, Luciana Rigoli, Mazzon, Emanuela, Salina, A, Giuseppe D’Annunzio, Patti, Giuseppa, Rigoli, L, Rosario Caruso, D'Annunzio, Giuseppe, Di Bella, C, Maghnie, M, Caruso, Rosario, Lombardo, Fortunato, Salina A., Caruso R., Di Bella C., Lombardo F., Aloi C., Mazzon E., Patti G., Rigoli L., D'Annunzio G., Salzano G., Maghnie M.   +43 more
core   +1 more source

Impact of Archwire Presence and Adhesive Removal Techniques on Enamel Crack Formation During Orthodontic Bracket Debonding: An In Vitro Study

Clinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Objectives Enamel cracks are a common complication following orthodontic bracket debonding and the removal of adhesives. This study investigated whether the presence of an archwire during debonding and the use of turbine (high‐speed) versus angle (low‐speed) tungsten carbide burs affect the number, length, or orientation of enamel cracks ...
Samane Bakhshi, Reza Ghorbanipour, Ghazaleh Ahmadizenouz, Seyedali Seyedmajidi, Maysam Mirzaie   +4 more
wiley   +1 more source

The Effect of N‐Acetyl Cysteine on Serum Lipid Profile and Heavy Metals in Women With Endometriosis Undergoing ICSI: A Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Endometriosis is associated with oxidative stress and heavy metal accumulation. This study evaluated whether N‐acetylcysteine (NAC) reduces serum heavy metals and improves lipid profiles in women with endometriosis undergoing fertility treatment.
Fatemeh Khorasani, Parvaneh Mirabi, Sedighe Esmaeilzadeh   +2 more
wiley   +1 more source