Results 111 to 120 of about 384 (136)

Phosphoproteomics Reveals the Wolframin-Calcium Axis as an Important Pathogenic Signaling Node in Primary Aldosteronism

Hypertension, 2023
Background: Aldosterone-producing adenoma (APA) is a benign adrenal tumor with autonomous aldosterone production which causes hypertension and excess cardiovascular risk. Protein phosphorylation regulates aldosterone secretion from adrenal cortical cells, but how signaling networks are remodeled in APA remains unknown.
Linqiang Ma, Shumin Yang, Yi Yang, Xiangjun Chen, Jun Yang, Yifan He, Qingfeng Cheng, Junlong Li, Bing Kang, Siying Tang, Aipin Zhang, Xiaoyu Shu, Xiaoyu Li, Hang Shen, Ying Jing, Ying Song, Qifu Li, Jinbo Hu   +17 more
openaire   +2 more sources

Functional effects of expression of wolframin-antisense transcripts in BRIN-BD11 β-cells

Biochemical and Biophysical Research Communications, 2003
Wolfram syndrome is a rare condition in which the pancreatic beta-cells of patients are selectively deleted during the early years of life by a non-autoimmune-mediated mechanism. The condition is associated with mutations in the gene encoding wolframin, suggesting that this protein exerts a critical, but currently unknown, function in beta-cells.
Noel Morgan
exaly   +3 more sources

P.1.03 N-terminal domain of Wolframin interactswith carboxypeptidase E

European Neuropsychopharmacology, 2005
Abstract of the ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe Nice, France March 3–6 ...
Luuk, H., Tools, U., Kõks, S., Vasar, E.   +3 more
openaire   +1 more source

A rare coding variant within the wolframin gene in bipolar and unipolar affective disorder cases

Neuroscience Letters, 1999
A recent report has shown that Wolfram syndrome carriers (heterozygotes) are 26-fold more likely to require psychiatric hospitalization compared with non-carriers, and that Wolfram syndrome heterozygotes may constitute approximately 25% of individuals hospitalized with depression and suicide attempts.
R A, Furlong, L W, Ho, J S, Rubinsztein, A, Michael, C, Walsh, E S, Paykel, D C, Rubinsztein   +6 more
openaire   +2 more sources

Novel mutations of wolframin: a report with a look at the protein structure

Clinical Genetics, 2010
A, Alimadadi, A, Ebrahim-Habibi, F, Abbasi, Mm, Amoli, F-A, Sayahpour, B, Larijani   +5 more
openaire   +2 more sources

wolframine

2014
openaire   +1 more source

wolframine

2009
openaire   +1 more source

Influence of wolframin expression on dopamine receptor functions

Intrinsic Activity, 2017
openaire   +1 more source

Distribution and localization of wolframin in adult human tissues

2008
DE FALCO, MARIA, A. Lucariello, L. De Luca, L. Manente, R. Tedesco, SELLITTI, ANNA, LAFORGIA, VINCENZA, A. De Luca   +7 more
openaire   +3 more sources

Pattern of expression of wolframin in human adult tissues

2007
De Falco M., Barletta C., Caliendo S., Manente L., Lucariello A., Coppola G., De Luca L., Laforgia V., De Luca A.   +8 more
openaire   +3 more sources