Results 61 to 70 of about 785,606 (262)

A Training Program Based on Learning by Design Approach to Develop Planning Skills for Science Teacher Trainees [PDF]

open access: yesمجلة بحوث التعليم والإبتكار
The research aimed to: reveal the effectiveness of a training program based on the learning by design approach to develop the planning skills of a science teacher during preparation.
Iman Badran Mohammad Ahmed   +3 more
doaj   +1 more source

Women in reproductive science [PDF]

open access: yesReproduction, 2019
This special issue on women in reproduction that acknowledges some of today's female trailblazers in the field of reproduction. When most of these women began their careers, there were few, if any, role models for them to follow. Most reproductive scientists were men; most general practitioners were men; most obstetricians and gynaecologists were men ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Editorial: Women in regulatory toxicology: 2021

open access: yesFrontiers in Toxicology, 2022
Marlene Ågerstrand   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Factors associated with change in arterial stiffness in patients with rheumatoid arthritis: the JointHeart study

open access: yesBlood Pressure
Background Rheumatoid arthritis (RA) predominantly affects women and is associated with hypertension and arterial stiffness. We explored factors associated with change in arterial stiffness in patients with RA treated with disease-modifying antirheumatic
Anja Linde   +6 more
doaj   +1 more source

A question of time

open access: yeseLife, 2018
How does a scientist balance establishing a career and starting a family?
Peter Rodgers
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Nomad scientists and the ones left behind

open access: yeseLife, 2017
To improve the diversity of the scientific workforce, we should not penalize researchers who are unable to move abroad for long periods.
Maya Bar, Barak Rotblat, Oded Rechavi
doaj   +1 more source

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