Results 81 to 90 of about 1,110,051 (352)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Women in Soil Science: Growing Participation, Emerging Gaps, and the Opportunities for Advancement in the USA

open access: yesSoil Science Society of America Journal, 2019
The soil science discipline has undergone significant changes since its establishment in the 1900s; from strong connections with agronomy to a broader focus on ecosystems, earth, and environmental sciences while also during this period experiencing a ...
K. Vaughan   +7 more
semanticscholar   +1 more source

2005

open access: yes, 2020
https://deepblue.lib.umich.edu/bitstream/2027.42/155371/2/objects.ziphttps://deepblue.lib.umich.edu/bitstream/2027.42/155371/4/metadata ...
University of Michigan. Women in Science and Engineering Program.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Presentation, 2006

open access: yes, 2020
https://deepblue.lib.umich.edu/bitstream/2027.42/155386/2/objects.ziphttps://deepblue.lib.umich.edu/bitstream/2027.42/155386/4/metadata ...
University of Michigan. Women in Science and Engineering Program.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Women in Biosensors Science

open access: yesBioengineering, 2023
From the first glucose biosensor from Updike and Hicks (1968), there was an explosion of research in biosensors for detecting a wide range of analytes [...]
openaire   +3 more sources

Oral History Interview, Graduate Women In Science (1241)

open access: yes, 2012
In their June 2012 interview with Troy Reeves and Vicki Tobias, Tina Hill, Tess Killpack, Christina Locke and Amanda Pertzborn discussed their participation in both Beta and National Chapters of GWiS (Graduate Women in Science).
Graduate Women In Science
core  

circa 2004

open access: yes, 2020
https://deepblue.lib.umich.edu/bitstream/2027.42/155372/2/objects.ziphttps://deepblue.lib.umich.edu/bitstream/2027.42/155372/4/metadata ...
University of Michigan. Women in Science and Engineering Program.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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