Results 71 to 80 of about 133,774,676 (282)

A Training Program Based on Learning by Design Approach to Develop Planning Skills for Science Teacher Trainees [PDF]

open access: yesمجلة بحوث التعليم والإبتكار
The research aimed to: reveal the effectiveness of a training program based on the learning by design approach to develop the planning skills of a science teacher during preparation.
Iman Badran Mohammad Ahmed   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Women in Science 2018-2019 ; v 15

open access: yes, 2019
undergraduate student periodicalDean Karen Bacon, the Mordecai D. and Dr. Monique C. Katz Dean of Undergraduate Arts and Sciences, for her support of the many programs and opportunities described herein that continue to empower Stern women in their ...
Department of Chemistry.   +3 more
core  

Editorial: Women in regulatory toxicology: 2021

open access: yesFrontiers in Toxicology, 2022
Marlene Ågerstrand   +3 more
doaj   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Factors associated with change in arterial stiffness in patients with rheumatoid arthritis: the JointHeart study

open access: yesBlood Pressure
Background Rheumatoid arthritis (RA) predominantly affects women and is associated with hypertension and arterial stiffness. We explored factors associated with change in arterial stiffness in patients with RA treated with disease-modifying antirheumatic
Anja Linde   +6 more
doaj   +1 more source

A question of time

open access: yeseLife, 2018
How does a scientist balance establishing a career and starting a family?
Peter Rodgers
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Nomad scientists and the ones left behind

open access: yeseLife, 2017
To improve the diversity of the scientific workforce, we should not penalize researchers who are unable to move abroad for long periods.
Maya Bar, Barak Rotblat, Oded Rechavi
doaj   +1 more source

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