Results 51 to 60 of about 2,005,308 (169)

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang, Fangjuan Hu, Xiaofeng Wang, Chunhan Tang, Chun Wang, Gefei Jiang, Chungang Zhao, Yin Zhang, Churong Li   +8 more
wiley   +1 more source

Overview and organization of Wood-Ljungdahl pathway, CODH, formate dehydrogenase, hydrogenase, and Rnf complex genes in sequenced and annotated C. difficile strains (ORF numbers according to their original annotation and position in the genome is given) and homologues in C. ljungdahlii (ORF number and identity on protein level against C. difficile strain 630 is given).

, 2013
Overview and organization of Wood-Ljungdahl pathway, CODH, formate dehydrogenase, hydrogenase, and Rnf complex genes in sequenced and annotated C. difficile strains (ORF numbers according to their original annotation and position in the genome is given ...
Melanie Straub (405398), Peter Dürre (405399), Michael Köpke (405397)   +2 more
core   +1 more source

Anaerobic Biohydrogenation of Isoprene by Acetobacterium wieringae Strain Y

mBio, 2022
Isoprene is a ubiquitously distributed, biogenic, and climate-active organic compound. Microbial isoprene degradation in oxic environments is fairly well understood; however, studies exploring anaerobic isoprene metabolism remain scarce, with no isolates
Huijuan Jin, Xiuying Li, Hongyan Wang, Natalie L. Cápiro, Xiaocui Li, Frank E. Löffler, Jun Yan, Yi Yang   +7 more
doaj   +1 more source

Unravelling the Chemolithoautotrophic Metabolism of the Carboxydotrophic Knallgas Bacterium Hydrogenophaga pseudoflava

Microbial Biotechnology, Volume 19, Issue 11, November 2026.
Proteomics of the aerobic carboxydotroph Hydrogenophaga pseudoflava across trophic conditions revealed that an unphysiological CO concentration causes a redox imbalance and stress response. CO dehydrogenase I and the membrane‐bound hydrogenase were essential for CO and H2 oxidation, respectively, whereas the soluble hydrogenase likely supports redox ...
Simon Grieshaber, Antonia Ebert, Pauline Kehr, Dominik L. Siebert, Ammar Al‐Shameri, Volker Sieber, Birgitta E. Ebert, Esteban Marcellin, Bastian Blombach   +8 more
wiley   +1 more source

An ancient pathway combining carbon dioxide fixation with the generation and utilization of a sodium ion gradient for ATP synthesis [PDF]

, 2012
Synthesis of acetate from carbon dioxide and molecular hydrogen is considered to be the first carbon assimilation pathway on earth. It combines carbon dioxide fixation into acetyl-CoA with the production of ATP via an energized cell membrane.
Kaster, Anne-Kristin, Meike Goenrich, Gerhard Gottschalk, Schmidt, Silke, Volker Müller, Hecker, M., Schmidt, S., John Vollmers, Silke Schmidt (46446), Anja Poehlein, Andrea Thürmer, Gerhard Gottschalk (34564), Vollmers, John, Thauer, R., Thurmer, A., Goenrich, Meike, Schuchmann, Kai, Michael Hecker, Meike Goenrich (174838), Thauer, Rudolf K., Rudolf K. Thauer (174856), Volker Müller (49251), Gottschalk, G., Hecker, Michael, Müller, Volker, Gottschalk, Gerhard, Bertsch, J., Daniel, R., Muller, V., Silke Schmidt, Birgit Voigt (174853), Poehlein, Anja, Schuchmann, K., Goenrich, M., Rudolf K Thauer, Andrea Thürmer (174844), Johannes Bertsch, Anne-Kristin Kaster (174829), Rolf Daniel (113374), Bertsch, Johannes, Johannes Bertsch (174847), Vollmers, J., Birgit Voigt, Kai Schuchmann (174850), Thürmer, Andrea, John Vollmers (174842), Rolf Daniel, Daniel, Rolf, Kaster, A., Anne-Kristin Kaster, Voigt, Birgit, Kai Schuchmann, Anja Poehlein (113372), Michael Hecker (51971), Voigt, B., Poehlein, A., Voigt Birgit, Thauer Rudolf K., Schmidt Silke, Kaster Anne-Kristin, Hecker Michael, Bertsch Johannes, Gottschalk Gerhard, Müller Volker, Thürmer Andrea, Daniel Rolf, Vollmers John, Poehlein Anja, Schuchmann Kai, Goenrich Meike   +69 more
core   +1 more source

MOESM4 of Development of a metabolic pathway transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii

, 2019
Additional file 4: Figure S4. Chromatograms of proteotypic peptides of selected proteins of the Wood–Ljungdahl pathway and the acetone biosynthesis pathway. Protein raw extract was prepared from C.
Sebastian de Vries (6682988), Gabriele Philipps (6682985), Stefan Jennewein (3469511)   +2 more
core   +1 more source

Demonstration of a new-to-nature pathway for ATP-driven reduction of CO2 to formate in vivo

, 2023
International audience• Direct CO2-reduction to formate is found in naturalmetabolic routes such as the Wood-Ljungdahl pathway. Thereaction is catalyzed by formate dehydrogenases (FDH),which transfer 2e– from H2, ferredoxins or NADPH to CO2.• However ...
Smith, Edward, Bar-Even, Arren, Perret, Alain, Dubois, Ivan, Döring, Volker, Erb, Tobias, J, Bouzon, Madeleine, He, Hai, Satanowski, Ari, Heinemann, Matthias, Marchal, Daniel, Petit, Jean-Louis   +11 more
core   +1 more source

Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy

Carbon Energy, Volume 8, Issue 10, October 2026.
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie, Jia Ouyang, Manu Suvarna, Xiangzhou Yuan, Matthew R. Hill, Uwe Bornscheuer, Huiyan Zhang, Yong Sik Ok   +7 more
wiley   +1 more source

Isolation and characterization of novel acetogenic strains of the genera Terrisporobacter and Acetoanaerobium

Frontiers in Microbiology
Due to their metabolic versatility in substrate utilization, acetogenic bacteria represent industrially significant production platforms for biotechnological applications such as syngas fermentation, microbial electrosynthesis or transformation of one ...
Tim Böer, Miriam Antonia Schüler, Alina Lüschen, Lena Eysell, Jannina Dröge, Melanie Heinemann, Lisa Engelhardt, Mirko Basen, Rolf Daniel, Anja Poehlein   +9 more
doaj   +1 more source

Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond, Ronny Amamoo, Fapianey J. Alexandre, Sewedo B. Ajisegiri, Menaka C. Thounaojam, Pamela M. Martin, Ravirajsinh N. Jadeja   +6 more
wiley   +1 more source