Results 51 to 60 of about 498,510 (259)

L’incidence des pratiques de conciliation travail–famille dans les milieux de travail canadiens : les milieux syndiqués sont-ils mieux pourvus et la situation s’améliore-t-elle ?

Revue Interventions Économiques, 2010
Work-life and work-family issues have been high on the agenda over recent years. In this paper, we wanted to see if the situation had gotten better over recent years and analysed the Workplace and Employment Survey (WES) of Statistics Canada.
Elmustapha Najem, Diane-Gabrielle Tremblay   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Balancing and Conflict Between Work and Family Life of Sandwiched Caregivers: A Scoping Review

Safety and Health at Work
The aim of this scoping review was to advance our understanding of the balancing and conflict between work and family life experienced by sandwiched caregivers.
Ayumi Honda, Mayo Ono, Takahiro Nishida, Sumihisa Honda   +3 more
doaj   +1 more source

HUBUNGAN ANTARA WORK-FAMILY BALANCE DENGAN KEPUASAN KERJA PADA TENAGA KEPENDIDIKAN DI UNIVERSITAS X

Jurnal Empati, 2020
Penelitian ini bertujuan untuk mengetahui hubungan antara work-family balance dengan kepuasan kerja pada tenaga kependidikan di universitas X. Kepuasan kerja didefinisikan sebagai hasil persepsi karyawan terhadap pekerjaannya yang dinilai penting.
Cindy Febria Tarigan, Ika Zenita Ratnaningsih   +1 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Contrasting Conceptions of Work–Family Balance and the Implications for Satisfaction with Balance during the COVID-19 Pandemic

Social Sciences
Pandemic-related changes, including the expansion of remote work and the closure of schools and daycare supports, posed unprecedented challenges to parents’ conceptions of their work and home routines. Drawing on interviews with 88 heterosexual partnered
Sejin Um, Anne Kou, Carolyn E. Waldrep, Kathleen Gerson   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source