Results 161 to 170 of about 140,062 (302)

Fluctuation-response relations for a two-stage population of spiking neurons stimulated by common noise. [PDF]

Biol Cybern
Dittrich L, Lindner B.
europepmc   +1 more source

Fluctuation Theorems and the Foundations of Statistical Mechanics

, 2010
In 1993 Evans, Cohen and Morriss described the first Fluctuation Theorem1. Fluctuation theorems describe the statistics of time averages of a generalized entropy production, namely the dissipation function.
Bernhardt, Debra, Reid, James, Evans, Denis J., Williams, Stephen R.   +3 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Promising Thermoelectric Performance of Janus Monolayer ZrBrI. [PDF]

Materials (Basel)
Wang J, Jiao W, Li Z, Liu H.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Quantitative analysis of light-induced ion segregation in mixed-halide perovskites. [PDF]

J Appl Crystallogr
Machovec P, Horák L, Dopita M, Neykova N, Landová L, Holovský J, Holý V.   +6 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Fluctuation-Mediated Model for Hydrogen-Inhibited N₂ Dissociation on Iron─Implications for Ambient Ammonia Electrosynthesis. [PDF]

J Phys Chem Lett
Hanslin SØ, Nørskov JK.
europepmc   +1 more source

Multiresponse Optimization through a Loss Function Considering Process Parameter Fluctuation

, 2005
A loss function approach to a multiresponse problem is considered, when process parameters are regarded as random variables. The variation of each response may be amplified through so called propagation of error (POE), which is defined as the standard ...
권준범, 전치혁, 김광재, 이종석, 이상호   +4 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source