Results 131 to 140 of about 20,779,634 (277)

Work ability and work quality as indicators for a longer and more productive working life.

open access: yes, 2009
Objective: In order to cope with the new challenges posed by globalization, job tasks and mental and physical workloads have to be re-designed to fit with levels of productivity in an ageing workforce.
Meloni M   +5 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Worker’s work ability index in the fruit and vegetable stands in Tehran in 2014

open access: yesپژوهان, 2015
Introduction: Now a days being involved in the jobs that are consistent with the capabilities and limitations, is one of the most important priorities of occupational health and company executives.
Mostafa Poyakian   +5 more
doaj  

[Job satisfaction and work ability index in nurses].

open access: yesLa Medicina del lavoro, 2015
Job satisfaction and work ability are important in the nursing profession to ensure good working conditions and to reduce work-related diseases and illness. Psychosocial factors such as social support and decision latitude (autonomy) could have a role in cardiovascular diseases, low back pain, injuries and sick leave.To evaluate work ability, job ...
Fiorella, Viola, Francesca, Larese Filon
openaire   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Assesment of work ability in physiotherapists [PDF]

open access: yes, 2020
Contemporary concepts of work ability emphasise the need to adjust work conditions to workers’ ability, bearing in mind that the psychophysical abilities of workers change over time.
Grozdek Čovčić, Gordana   +6 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Relationship between Work Ability Index and Fatigue among Iranian Critical Care Nurses

open access: yesInternational Journal of Occupational Hygiene, 2018
Nurses have always been considered as a unique working group because of the physically and mentally demanding tasks they bear at work. Such a working condition exposes them to a high risk of fatigue, which could influence their work ability.
EHSAN GAROSI   +4 more
doaj  

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