Results 151 to 160 of about 20,779,634 (277)

Analisa hubungan tingkat kelelahan terhadap Work Ability Index (WAI) melalui kuesioner Swedish Occupational Fatigue Inventory (SOFI) [PDF]

open access: yes, 2017
Kelelahan merupakan salah satu faktor penting yang berpengaruh terhadap kemampuan kerja. Kelelahan berpengaruh secara berbeda sesuai dengan jenis pekerjaan yang dilakukan, yaitu mental dan fisik.
Yuliani, Estherina
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Study of relationship between Safety attitude and knowledge and The work ability index (A case study in one of the big hospitals in Tehran)

open access: yesSalāmat-i kār-i Īrān, 2018
Background and aims: Knowledge of safety attitude is very important for managers of organizations, because it can be used to predict their employee safety behaviors.
Roghayeh Soleimani   +3 more
doaj  

Validity and reliability of the Brazilian version of the Work Ability Index questionnaire.

open access: yesRevista de saude publica, 2009
OBJETIVO: Evaluar la validez y la confiabilidad de la versión brasilera del índice de capacidad para el trabajo. MÉTODOS:Estudio transversal con muestra de 475 trabajadores de empresa del sector eléctrico en el estado de Sao Paulo (fueron diez municipios en Campinas y región, en Sureste de Brasil), realizado en 2005.
Martinez, Maria Carmen   +2 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Capacidade para o trabalho em indivíduos com lesões músculo-esqueléticas crônicas

open access: yesRevista de Saúde Pública
OBJETIVO: Avaliar o impacto de fatores pessoais, do trabalho e da lesão na capacidade funcional dos trabalhadores com e sem história de acometimento de lesões músculo-esqueléticas relacionadas ao trabalho, através da aplicação do índice de capacidade ...
IAP Walsh   +5 more
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Transtheoretical Model Is Better Predictor of Physiological Stress than Perceived Stress Scale and Work Ability Index among Office Workers. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Marin-Farrona M   +5 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

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