Results 61 to 70 of about 938,233 (243)

Analytical evaluation of work ability index and its determining factors among workers of a car manufacturing industry

Salāmat-i kār-i Īrān, 2012
Background and aims : The ability of work is the basis of well-being for all of us. Many factors affect the work ability such as work and work condition, work organization and human resource. The aim of this study was to assess the work ability among car
M Eyvazlou, A Mazloumi, A.A Farshad, F Hoseini   +3 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Agentes de limpeza terceirizados: entre o ressentimento e o reconhecimento

Revista Brasileira de Saúde Ocupacional
Resumo Objetivo: analisar a percepção sobre a atividade de trabalho dos agentes de limpeza terceirizados de uma faculdade pública e determinar seu índice de capacidade para o trabalho.
Sandra Francisca Bezerra Gemma, Marta Fuentes-Rojas, Maurílio José Barbosa Soares   +2 more
doaj   +1 more source

Work Ability Index (WAI) values in a sample of the working population in Poland

Annals of Agricultural and Environmental Medicine, 2019
Ability to work is most often defined as a relationship between a person's resources and requirements specific to a particular type of work. It is the result of interaction between job requirements in terms of physical and mental strain, capabilities and skills of the employee, as well as his/her health condition and own evaluation of functioning in a ...
Grzegorz Juszczyk, Aleksandra Czerw, Urszula Religioni, Dominik Olejniczak, Jolanta Walusiak-Skorupa, Tomasz Banas, Marcin Mikos, Anna Staniszewska   +7 more
openaire   +5 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Relationship between Mental Workload Index and Work Ability Index in a Food Industry

Archives of Occupational Health, 2018
Background: Spending a significant part of the daily in workplace has led to reduction in the time of rest and recreation of people. Therefore, considering the importance of the potential effect of mental work load on work ability, the present study was ...
Nafiseh Azimi, Ghasem Hesam, Farideh Khosravi, Majid Motamedzadeh, Zahra Moradpour   +4 more
doaj  

Workplace interventions to improve work ability: A systematic review and meta-analysis of their effectiveness

Scandinavian Journal of Work, Environment & Health, 2018
OBJECTIVE: Extended working lives due to an ageing population will necessitate the maintenance of work ability across the life course. This systematic review aimed to analyze whether workplace interventions positively impact work ability.
Jodi Oakman, Subas Neupane, Karin I Proper, Natasha Kinsman, Clas-Håkan Nygård   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source