Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Building Health Equity Research Capacity in Myanmar Through a Virtual, Mentor-Based Training Program. [PDF]
Sein TT +8 more
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Scarcity-Coefficient Gated Projection Reinforcement Learning for Planning-Layer Capacity Activation in Emergency Wireless Networks. [PDF]
Ma J, Liu P, Ma H, Lu G, Zhang Y.
europepmc +1 more source
Battery Pack for IoT Devices in a Harsh Outdoor Environment. [PDF]
Ševčík P +3 more
europepmc +1 more source
Electroconvulsive Therapy Refusal in Severe Psychosis: Navigating Capacity, Surrogate Decision-Making, and Ethical Duty. [PDF]
Perera K +4 more
europepmc +1 more source
Closing the Empirical Loop: Autonomous AI Agents Conduct End-to-end Research With Human Participants. [PDF]
Wehr G +6 more
europepmc +1 more source
Developing an inclusive research (methods) strategy for the Manchester Biomedical Research Centre and Clinical Research Facility. [PDF]
Coleman A +6 more
europepmc +1 more source
Assessment of emergency management capabilities for public health emergencies in China. [PDF]
Zhou M.
europepmc +1 more source
[Evaluation of the work capacity of tuberculosis patients].
openaire +1 more source

