Results 131 to 140 of about 1,695,856 (309)

Impact of Work Overload Work Stress and Work Discipline on Employee Job Satisfaction

open access: yesJurnal Pamator
This research aims to determine the relationship between work overload, work stress, and work discipline in influencing job satisfaction. The study employs a quantitative approach as the research method.
Irma Galuh Septiany   +2 more
doaj   +1 more source

PENGARUH DISIPLIN KERJA DAN BUDAYA ORGANISASI TERHADAP KOMITMEN ORGANISASI PADA KARYAWAN PT. SUPERNOVA [PDF]

open access: yes, 2015
Alfiyah Nur Fadhilah, 2016; The Influence of Work Discipline and Organizational Culture Against Organizational Commitments at PT. Supernova Cikarang. Skripsi: Jakarta: Concentration in Human Resource Management, Management Studies Program, Department of
FADHILAH, ALFIYAH NUR
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Impact of Work Environment, Discipline, and Motivation on Honorary Staff Performance at Surabaya Maritime Polytechnic

open access: yesIJEBD (International Journal of Entrepreneurship and Business Development)
Purpose: This study aims to analyze the influence of work environment, work discipline, and work motivation on the performance of Honorary Staff at Surabaya Maritime Polytechnic.
Elok Damayanti
doaj   +1 more source

Pengaruh Individu dan Organisasi terhadap Disiplin Kerja (Studi pada PT. Bank “X” Cabang “Y” Malang) [PDF]

open access: yes, 2010
Work discipline is the condition desired by organization. Work discipline will never be happened automatically, but should be shaped by many factors, both individual and organizational factors.
Habsyi, T. A. (Taher)   +2 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Positive Behavior Support and Student Response to the Behavior Education Program [PDF]

open access: yes, 2009
School-wide positive behavior supports (SWPBS) is an evidence-based systematic approach that views problem behaviors in a positive, preventative manner.
Paolella, Kate
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Work Discipline on Employee Performance Through Work Productivity

open access: yesAdvances in Human Resource Management Research
Purpose: This study examines the effect of work productivity on employee performance at PT Paguntaka Cahaya Nusantara Papua and West Papua Branch. Research Design and Methodology: Data was collected using a cross-sectional research design through a survey involving employees from various departments.
Cut Yeni Tasya   +2 more
openaire   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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