Results 141 to 150 of about 95,733 (264)
The discipline of the madman: power, madness and discipline in Michel Foucault's work
EikasíaThis paper studies some of the fundamental concepts of Michel Foucault's work and the interconnections between them. Specifically, it attempts to establish the relationship between power, discipline and madness.
Elsa Rodríguez López
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Discipline diversity and agency : pedagogic practice and dispositions to learning
, 2010 What, then, makes discipline good? .. .is not discipline-all discipline-essentially a restraint, a limitation imposed on man's behaviour? If life is good, how can it be good to bridle it, to constrain it, to impose limits that it cannot overcome ...
Watkins, Megan (R10473)
core
Partnering for success: Marrying social work with religion and culture
, 2001 The educational landscape in South Africa is changing rapidly in response to, amongst other factors, economic market conditions in the country (De Bard & Peck, 2000:3).
Partab, R, Kasiram, Ml
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Attitudes to parenting practices and child discipline [PDF]
, 2014 This qualitative research report outlines the findings of focus groups held to explore parents’ views about parenting practices and approaches to child discipline.
Prince, J +11 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2023 The motivation behind this examination is to figure out the issues related to employee performance, especially those related to the influence of work stress, work environment, and work discipline at PT. Artindo Artamas. The data survey and collection was
Silaswara, Diana, Kusuma, Aderia
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source