Results 141 to 150 of about 1,698,497 (308)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Jurnal Manajemen Agribisnis dan AgroindustriThe most important part in realizing a company so that the activities carried out can be organized and appropriate are its human resources. Employees in the company must have the ability and knowledge so that the company runs optimally. Aspects
Muhammad Fiqri, Andina Mayangsari
doaj +1 more source
The International Halley Watch: A program of coordination, cooperation and advocacy [PDF]
To prevent a repetition of the lack of reporting and dissemination of the data obtained during the 1910 observations of Comet Halley, a mechanism is proposed for coordinating the work of scientists and amateurs, including government, industrials, and ...
Friedman, L., Newburn, R. L.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Ownership concentration and market discipline in European banking: Good monitoring but bad influence? [PDF]
We investigate the impact of banks’ ownership concentration on the effectiveness of shareholders’ market discipline. More precisely, we first assess whether the ability of the distance to default to predict banks’ financial distress is affected by the ...
Olivier BROSSARD (LEREPS-GRES) +1 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Pengaruh Work Motivation, Work Discipline dan Training Terhadap Employee Work Productivity
Al-Kharaj: Jurnal Ekonomi, Keuangan & Bisnis SyariahThe success of a company is measured by how optimally it uses existing resources to achieve high productivity. This research aims to find out how much influence work motivation, work discipline and training have on the work productivity of PT employees. IEI. This type of research is quantitative research analyzed using statistics.
Tri Mulyani Kartini +2 more
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source