Results 111 to 120 of about 2,558,450 (356)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Does the Market Help Workers Balance Work-Family Conflict? [PDF]

open access: yes
We use data from the Canadian Workplace and Employee Survey (1999-2002) to assess the take-up of family-friendly benefits that are provided by employers.
Ferrer, Ana, Gagné, Lynda
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Predicting Work-Family and Familywork Conflict from Work and Family Domain: A Longitudinal Study

open access: yesInternational Journal of Management Studies, 2012
Although work-family conflict studies are available in Malaysia, most rely on cross-sectional design and focus on women. This study uses the longitudinal design on a heterogeneous sample which is aimed to enhance the understanding of the antecedents of ...
Zaiton Hassan, Hana Hamidi
doaj  

Pengaruh Work Family Conflict, Family Work Conflict, dan Work Life Balance Terhadap Kinerja Karyawan

open access: yesJurnal Ekonomi Bisnis, Manajemen dan Akuntansi (JEBMA)
Masalah penelitian ini adalah terjadinya penurunan kinerja karyawan wanita pada PT BBC. Tujuan penelitian ini dilakukan untuk mengetahui pengaruh work family conflict, family work conflict, dan work life balance terhadap kinerja karyawan wanita pada PT BBC.
Aileen Fransisca   +4 more
openaire   +1 more source

Single Mothers, Social Capital, and Work-Family Conflict [PDF]

open access: yes
The purpose of this paper is to examine work-family conflict among low-income, unmarried mothers. I examine how social capital affects work-family conflict and how both social capital and work-family conflict affect employment.
Teresa Ciabattari
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Community Demands and Resources and Work-Family Conflict: Case Study in Kuching Sarawak

open access: yesInternational Journal of Management Studies, 2014
Most studies on work-life balance only examine work and family domains. While work is the only role in its domain, life consists of many aspects besides family. However, research on other roles is still very limited.
Zaiton Hassan   +2 more
doaj  

Home - About - Disclaimer - Privacy