Results 121 to 130 of about 2,573,382 (308)

Employees’ Financial Insecurity and Health: The Underlying Role of Stress and Work–Family Conflict Appraisals

, 2018
Data from two longitudinal samples were utilized to elucidate underlying mechanisms of the well‐established relationship between financial insecurity and health outcomes, stemming from the theoretical rationale of conservation of resources and cognitive ...
Matthews, Russell A., Odle-Dusseau, Heather N., Wayne, Julie H.   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Analisis Pengaruh Konflik Peran Ganda, Disiplin Kerja, dan Lingkunganpkerja Terhadapnkinerja Karyawanp PT. Globalindopintimates di Klaten [PDF]

, 2019
The research to find out and describe the influence of either simultaneously of partial work-family conflict, work discipline and work environtment. The population was all employees PT. Globalindo Intimates Klaten totaled 1300.
Kustiyah, E. (Eny), Sulisvi, S. (Sulisvi), Widayanti, R. (Rochmi)   +2 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

PENGARUH KOMPENSASI, WORK-FAMILY CONFLICT, DAN STRES KERJA TERHADAP KEPUASAN KERJA SALESMAN PT CAHAYA SAKTI FURINTRACO (OLYMPIC GROUP) [PDF]

, 2015
WISESA ALIF PRIYAMBODO RAMADHAN. The Impact of Compensation, Work-Family Conflict, and Work Stress on Salesman Job Satisfaction in PT Cahaya Sakti Furintraco (OLYMPIC GROUP). Faculty of Economics State University of Jakarta. 2015.
RAMADHAN, WISESA ALIF PRIYAMBODO
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A conciliação de papéis profissionais e familiares: o mecanismo psicológico de spillover

Psicologia: Teoria e Pesquisa
A maioria dos estudos sobre o tema da conciliação entre a vida profissional e familiar tem assumido uma perspectiva negativa e de conflito, focando as dificuldades nesta conciliação.
Marisa Matias, Anne Marie Fontaine
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Analisis Pengaruh Work Family Conflict dan Role Stress terhadap Komitmen Organisasional Karyawan [PDF]

, 2016
Jumlah villa di Bali yang semakin berkembang, menuntut The Clubs Villas memiliki keunggulan kompetitif dalam bersaing dengan memperhatikan karyawan, melalui kejadian masalah-masalah dalam pengelolaan sumber daya manusia khususnya dalam membina komitmen ...
Sudibya, G. A. (Gede), Yantha, G. P. (Gede)   +1 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source