Results 131 to 140 of about 2,573,382 (308)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Job, Family and Individual Factors as Predictors of Work-Family Conflict [PDF]

open access: yes, 2008
The growing interest in understanding fully the interface of work and family roles and their antecedents has stimulated the development of a predictive model of work-family conflict.
Ahmad, Aminah
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Social Work with Families and Work-Family Conflict

open access: yes, 2013
The article analyses the direct and modulating effects of family support on burnout in the work-family conflict in Spanish middle-class families. The analysis has been separated by gender in order to better examine differences. Direct relationships in the data show that family support is negatively related to the two subscales of burnout, especially in
Oscar Segovia, Amparo   +2 more
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Family Supportive Supervision Around the Globe

open access: yes, 2018
Family-supportive supervision (FSS) refers to the degree to which employees perceive their immediate supervisors as exhibiting attitudes and behaviors that are supportive of their family role demands (Hammer, Kossek, Zimmerman, & Daniels, 2007; Kossek ...
Hammer, Leslie B.   +2 more
core  

Analisis Work Family Conflict, Stres Kerja Dan Kinerja Wanita Berperan Ganda Pada Yayasan Compassion East Indonesia [PDF]

open access: yes, 2015
The research was conducted with the objective of verifying the influence of Work Family Conflict consists of work to family conflict and family to work conflict and with job stress to analyze performance of dual role women in the foundation Compassion ...
Roboth, J. Y. (Jane)
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

The New Dad: A Portrait of Today's Father [PDF]

open access: yes, 2015
Over the last six years, the Boston College Center for Work & Family (BCCWF) has completed a series of research studies on the changing face of fatherhood in America.
Brad Harrington   +3 more
core  

Bidirectional nature of work family conflict: The antecedents and outcomes of work to family conflict and family to work conflict

open access: yes, 2021
The aim of the present study was to investigate the bidirectional nature of work family conflict: work to family conflict (WFC) and family to work conflict (FWC). Antecedents and outcomes of both directions were examined. Antecedents of WFC were categorized as work stressors which included role demands, injustice and autonomy whereas outcomes of work ...
openaire   +1 more source

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