Results 141 to 150 of about 2,558,450 (356)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Job, Family and Individual Factors as Predictors of Work-Family Conflict [PDF]

, 2008
The growing interest in understanding fully the interface of work and family roles and their antecedents has stimulated the development of a predictive model of work-family conflict.
Ahmad, Aminah
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Gender role orientation of husbands and work-family conflict of wives in dual-earner families [PDF]

, 1999
This study examined the intensity of work-family conflict experienced by married working women, the gender role orientation of their husbands, and the relationship between husbands' gender role orientation and wives' work-family conflict.
Ahmad, Aminah
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Social Work with Families and Work-Family Conflict

, 2013
The article analyses the direct and modulating effects of family support on burnout in the work-family conflict in Spanish middle-class families. The analysis has been separated by gender in order to better examine differences. Direct relationships in the data show that family support is negatively related to the two subscales of burnout, especially in
Oscar Segovia, Amparo, Segado Sánchez-Cabezudo, Sagrario, López Peláez, Antonio   +2 more
openaire   +1 more source

Hubungan Antara Work-family Conflict Dengan Subjective Well-being Pada Perawat Rumah Sakit Panti Wilasa “Dr. Cipto” Semarang [PDF]

, 2014
Perkembangan dan pertumbuhan ekonomi yang sangat pesat beberapa tahun terakhir ini mendorong wanita untuk bepartisipasi dalam dunia kerja. Salah satu profesi yang sebagian besar digeluti oleh wanita, memiliki tanggung jawab yang berat, dan memiliki jam ...
Nurtjahjanti, H. (Harlina), Pratiwi, V. K. (Valentina)   +1 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Role Conflict and Coping Behaviour of Married Working Women [PDF]

, 1995
This study examined the conflict that married women experienced between work and family roles, and analysed the coping behaviour. Data from 82 professional women from six research institutes revealed that married women experienced work-family conflict ...
Ahmad, Aminah
core