Results 81 to 90 of about 1,229,730 (302)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Difficulties in the work-from-home setting, coping mechanisms and work performance among elementary teachers in Subic district

open access: yesHo Chi Minh City Open University Journal of Science - Social Sciences
This study involved 228 teachers assigned to public elementary schools in the Division of Zambales, Subic District, Philippines, during the SY 2020 - 2021 and focused on the profile, experiences in the work-from-home setting as encountered by teachers ...
Ivy Casupanan, Jeffrey Reyes
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Business Travellers' Connections to Home: ICTs Supporting Work-life Balance [PDF]

open access: yes, 2016
This paper examines the role of information communication technology in enabling connections to home for work related travellers. Although digital connectivity for work related tasks are well researched, the use of digital technology for home ...
Marouda, M.   +7 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The Relationship between Remote Work and Job Satisfaction: A Literature Review

open access: yesBAR: Brazilian Administration Review
Objective: to review the remote work arrangements (RWA) literature and propose a framework of the effects on job satisfaction, incorporating mediators and moderators that explain remote work nuances through the lens of self-determination and ...
Heloise Helena Berger Ploszaj   +2 more
doaj   +1 more source

Home supervision requirements : messages from research

open access: yes, 2012
This briefing summarises key findings of research on Home Supervision Requirements (HSRs) in Scotland. It summarises knowledge from existing research and incorporates new evidence from a recently concluded study exploring young people's, parents’ and ...
Gadda, Andressa, Fitzpatrick, John Paul
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Remote Work and Technology. A Brief History and Evolutions in E.U and Romania [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
The paper below searches for the basics of the work at distance in the few successive decades life-time of the information technology. The reader will here meet dates and data arranged and correlated notions and evolutions introduced as simultaneously ...
Dalina-Maria Andrei
doaj  

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