Results 81 to 90 of about 14,161,319 (386)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

PENGARUH UPAH TERHADAP MOTIVASI KERJA KARYAWAN HOME INDUSTRY GAMELAN MITRA JAYA MAGETAN

open access: yesEQUILIBRIUM: Jurnal Ilmiah Ekonomi dan Pembelajarannya, 2016
This study aims to determine the remuneration to the home industry Gamelan Mitra Jaya Magetan, to know the motivation of employees working at home industry Gamelan Mitra Jaya Magetan as well as to determine whether or not the influence of remuneration on
Nisa Nur Hidayah
doaj   +1 more source

Islamic Leadership, Islamic Work Culture, and Employee Performance: The Mediating Role of Work Motivation and Job Satisfaction

open access: yes, 2020
This study aims to examine the influence of Islamic leadership and Islamic work culture on employee performance through work motivation and job satisfaction.
S. D. Astuti, Ali Shodikin, Maaz Ud-Din
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Use of Project Work to Promote Students’ Motivation toward English Class among 10 Graders of State Senior High School 1 Purworejo [PDF]

open access: yes, 2012
This classroom action research aimed at using project work to promote the students’ motivation toward English class among 10 graders of State Senior High School 1 Purworejo in the Regency of Purworejo.
Hendarto, Eko
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Motivasi Kerja Pegawai Di Kantor Keyahbandaran Utama Makassar

open access: yesJurnal Ilmiah Manajemen dan Bisnis, 2017
This study aims to determine the motivation of employees at the Office Kesyahbandaran Utama Makassar. The type of research is descriptive, with population of all employees at Kesyahbandaran Utama Makassar Office amounting to 265 people / employees ...
Muh Nasrullah   +3 more
doaj   +1 more source

Motivation to work performance [PDF]

open access: yes, 2015
Bakalářská práce se zabývá vztahem mezi motivací a pracovním výkonem. Cílem bakalářské práce je analýza motivace k pracovnímu výkonu ve vybraném podniku a současně návrh praktických doporučení pro zlepšení, se zaměřením pozornosti na několik klíčových ...
Sulanová Karolína
core  

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