Results 121 to 130 of about 8,867,877 (306)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Moderating effects of resilience on the relationship between self-leadership and innovative work behavior

open access: yesSustainable Futures
This study aimed to examine the moderating effects of resilience (RES) on the association between self-leadership (SEL) and innovative work behavior (IWB) of employees. The study sample consisted of 250 warehouse workers in the logistics business.
Na-Nan Khahan   +3 more
doaj   +1 more source

Work-Family Interaction, Self-Perceived Mental Health and Burnout in Specialized Physicians of Huelva (Spain): A Study Conducted during the SARS-CoV-2 Pandemic. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Gago-Valiente FJ   +9 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

TANF and Higher Education [PDF]

open access: yes, 2010
Welfare reforms in 1996 created the Temporary Assistance for Needy Families Block Grant program (TANF). Under the assumption that a job will provide recipients with a path to self-sufficiency, this program focuses primarily on putting them to work ...
Hardy, Leah
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

The Limits of Relocation: Employment and Family Well-Being Among Former Madden/Wells Residents [PDF]

open access: yes, 2010
Explores the effects of moving from distressed public housing to safer, mixed-income developments and new work requirements on residents' employment, income, and self-sufficiency.
Diane K. Levy
core  

Explicit characterization of the identity configuration in an Abelian Sandpile Model

open access: yes, 2008
Since the work of Creutz, identifying the group identities for the Abelian Sandpile Model (ASM) on a given lattice is a puzzling issue: on rectangular portions of Z^2 complex quasi-self-similar structures arise. We study the ASM on the square lattice, in
Andrea Sportiello   +17 more
core   +1 more source

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