Results 151 to 160 of about 136,179,624 (307)
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Working mothers and their multivoiced self
Since the 1960's, work has been a goal for Brazilian middle class women. In contrast, mothers of lower-income groups have always needed to work. This qualitative study investigated the meaning of motherhood, child care and work among 28 working mothers of different social classes. In order to do so, interviews and focus groups were conducted.
openaire +2 more sources
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Perceptions of family functioning and self-concept in adolescent anorexia nervosa
Authors have highlighted the importance of the family for the development of positive self-concept and identity, not only in mental health research but also in various developmental and social psychology fields.
Halse, Christine +3 more
core
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
The Double-Edged Sword Effects of Teacher-AI Collaboration on Work Engagement: A Self-Determination Theory Perspective. [PDF]
Sun J, Xing Y, Yuan G, Cai Q.
europepmc +1 more source
Die Betrachtung von Selbstverwirklichung und sinnvoller Arbeit einschließlich ihrer Potenziale für die die persönliche Entwicklung lassen sich bis hin zu den griechischen Philosophen zurück datiertieren. Aristoteles beschrieb eine ethisch sinnvolle, eudaimonische Lebensweise, die durch selbstbestimmte Aktivitäten und die Verwirklichung des höchsten ...
openaire +1 more source

