Results 91 to 100 of about 4,290,560 (312)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Mapping community pathways to employment for youth with disabilities—a realist review

Frontiers in Public Health
Background and objectivesYouth with disabilities face significant challenges in accessing employment and transitioning from school-to-work settings. Youth in intersectional contexts face additional barriers.
Amelia Hagelstam-Renshaw, Roberta Cardoso, Jinan Zeidan, Ebrahim Mahmoudi, Linda Nguyen, Eleni Philippopoulos, Keiko Shikako   +6 more
doaj   +1 more source

Understanding Evidence-Based Interventions for Cross-Cultural Group Work: A Learning Analytics Perspective [PDF]

, 2016
As the numbers of international students worldwide continue to rise, one common challenge is how best to socially integrate diverse groups of students.
Mittelmeier, Jenna
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Navigating urban mobility: Mobility attitudes and travel mode choices in Dubai and Lahore

Transport Economics and Management
Understanding the complexities of urban travel behaviors is essential for fostering sustainable mobility systems. This study examines the impact of socio-economic factors, attitudinal variables, and urban characteristics on travel mode choices for ...
Abdul Ghaffar Chaudhry, Houshmand Masoumi, Hans-Liudger Dienel, Atif Bilal Aslam, Mariam Shahnaz, Muhammad Ahmad, Mehtab Hussain   +6 more
doaj   +1 more source

Legislative change enabling use of early part-time sick leave enhanced return to work and work participation in Finland

Scandinavian Journal of Work, Environment & Health, 2017
OBJECTIVES: The aim of the study was to assess the effectiveness of the use of part-time sick leave at the early (first 12 weeks) stage of work disability due to mental disorder or musculoskeletal disease on sustained return to work (RTW) and overall ...
Eira Viikari-Juntura, Lauri J Virta, Johanna Kausto, Ilona Autti-Rämö, Kari-Pekka Martimo, Mikko Laaksonen, Taina Leinonen, Kirsti Husgafvel-Pursiainen, Alex Burdorf, Svetlana Solovieva   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Duration of Absence from Work Is Related to Psychopathology, Personality, and Sociodemographic Variables in a Longitudinal Cohort

Frontiers in Psychiatry, 2017
ObjectiveTo examine, in a non-clinical sample, the association of psychopathology, personality, sociodemographic information, and psychosocial indicators of non-occupational functioning with the duration of absence from work in the past 12 months.MethodA
Alex Gamma, Roman Schleifer, Ingeborg Warnke, Vladeta Ajdacic-Gross, Wulf Rössler, Wulf Rössler, Jules Angst, Michael Liebrenz   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Participation by men and women in off-farm activities: An empirical analysis in rural northern Ghana [PDF]

"Using survey data from the Upper East region of Ghana collected in 2005, the paper evaluates the household- and community-level factors influencing women's and men's decisions to participate in off-farm activities, either in the off-farm labor market or
McCarthy, Nancy, Sun, Yan
core