Results 121 to 130 of about 4,290,560 (312)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The effective participation of the audience in the production of news: encouraging opportunities through data journalism [PDF]

open access: yes, 2018
Digital tools allow and encourage users "to participate in the creation and circulation of media” (Lewis, 2012). This participation can be considered as a remedy against the growing disconnection between journalism and citizens, also as a formula for a ...
Blanco-Castilla, Elena Pilar   +1 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Self-rated work ability predicts return to work after occupational rehabilitation

open access: yesFrontiers in Rehabilitation Sciences
IntroductionWork ability assessments are important for planning, targeting, and executing occupational rehabilitation programs. The aim of the study was to examine whether a one-item self-rated Work Ability Score (WAS), assessed before and after ...
Chris Jensen   +6 more
doaj   +1 more source

Documenting Work: From Participant Observation to Participant Tracing [PDF]

open access: yes, 2015
This paper explores the methodological aspects of studying distributed work by focusing on the more tangible aspects of this work, namely documents. We show how 1) researchers should engage in an initial mapping of documents before starting to track them; 2) the ongoing flow of virtual organizing only becomes apparent by triangulating the digital flow ...
openaire   +1 more source

Bolder Together 2: Building Grassroots Movements for Change [PDF]

open access: yes, 2016
California's demographics are changing fast, but rates of voting and civic participation haven't kept up. In four rapidly growing counties across the state, a group of funders is working with local organizations to support diverse communities to lift up ...
Cathy Cha, William H. Woodwell, Jr.
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Assessing the Evidence About Work Support Benefits and Low-Income Families [PDF]

open access: yes, 2011
Reviews research on factors affecting participation in work supports such as Medicaid, Children's Health Insurance, Supplemental Nutrition Assistance, and childcare subsidy programs; the programs' payoff, and state benefits of modernized delivery ...
Gregory Mills   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Empowering Women through Education and Influence: An Evaluation of the Indian Mahila Samakhya Program [PDF]

open access: yes
This paper shows that participation in a community-level female empowerment program in India significantly increases participants' physical mobility, political participation, and access to employment.
Arends-Kuenning, Mary P.   +2 more
core  

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