Results 101 to 110 of about 1,158,172 (358)

Predicting Workflow Task Execution Time in the Cloud Using A Two-Stage Machine Learning Approach

open access: yesIEEE Transactions on Cloud Computing, 2020
Many techniques such as scheduling and resource provisioning rely on performance prediction of workflow tasks for varying input data. However, such estimates are difficult to generate in the cloud. This paper introduces a novel two-stage machine learning
Thanh-Phuong Pham   +2 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Beyond the borders: Lessons from various industries adopted in anesthesiology

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2019
Since the first public demonstration of anaesthesia in Boston, USA which happened around 172 years back, the field of anesthesiology has rapidly progressed, with many developments that have improved the quality and safety of anesthesia care.
Subramanyam S Mahankali, Priya Nair
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

GRIDCC: Real-time workflow system [PDF]

open access: yes, 2007
The Grid is a concept which allows the sharing of resources between distributed communities, allowing each to progress towards potentially different goals.
Akram, A   +7 more
core  

From Raw Data to FAIR Data: The FAIRification Workflow for Health Research

open access: yesMethods of Information in Medicine, 2020
Background FAIR (findability, accessibility, interoperability, and reusability) guiding principles seek the reuse of data and other digital research input, output, and objects (algorithms, tools, and workflows that led to that data) making them findable,
Ali Anil Sinaci   +13 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

IMPROVING INSTITUTIONAL SERVICES THROUGH UNIVERSITY ERP: A STUDY OF THE ACADEMIC PLANNING MODULE DEVELOPMENT AT SEEU

open access: yesSEEU Review, 2017
Enterprise Resource Planning (ERP) systems are used by universities to handle the academic services and business processes while providing enhanced experience and services to students.
Chaushi Blerta Abazi   +2 more
doaj   +1 more source

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