Results 101 to 110 of about 1,099,627 (374)

Designer: a tool to design and model workflows [PDF]

open access: yes, 1997
This work presents the methodological and technical issues for the Designer tool in the OBJECTFLOW Workflow Management System. This tool provides to the user the possibility to model and design workflow diagrams from Business Process of a corporation ...
Botella López, Pere, Camilo, Ocampo
core   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

Predicting Workflow Task Execution Time in the Cloud Using A Two-Stage Machine Learning Approach

open access: yesIEEE Transactions on Cloud Computing, 2020
Many techniques such as scheduling and resource provisioning rely on performance prediction of workflow tasks for varying input data. However, such estimates are difficult to generate in the cloud. This paper introduces a novel two-stage machine learning
Thanh-Phuong Pham   +2 more
semanticscholar   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Introducing time-lapse for flexible embryo assessment in in vitro fertilization: implications for grading confidence and workflow efficiency

open access: yesF&S Reports
Objective: To compare embryologists’ confidence levels and grading concordance when assessing embryo morphology using time-lapse images vs. traditional direct observation under a microscope. Design: Prospective study. Subjects: Six embryologists on staff
Alicia Picou, M.S.   +4 more
doaj   +1 more source

SMORE: Synteny Modulator of Repetitive Elements

open access: yesLife, 2017
Several families of multicopy genes, such as transfer ribonucleic acids (tRNAs) and ribosomal RNAs (rRNAs), are subject to concerted evolution, an effect that keeps sequences of paralogous genes effectively identical.
Sarah J. Berkemer   +3 more
doaj   +1 more source

SFDL: MVC Applied to Workflow Design [PDF]

open access: yes, 2010
Process management based on workflow systems is a growing trend in collaborative environments. One of the most notorious areas of improvement is that of user interfaces, especially since business process definition languages do not address efficiently ...
Aguirre Herrera, Sandra   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

A Workflow for Global Sensitivity Analysis of PBPK Models

open access: yesFrontiers in Pharmacology, 2011
Physiologically based pharmacokinetic models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can ...
Kevin eMcNally   +2 more
doaj   +1 more source

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