Results 111 to 120 of about 1,158,460 (311)

Planning with Global Constraints for Computing Infrastructure Reconfiguration [PDF]

open access: yes, 2012
This paper presents a prototype system called SFplan- ner which uses an automated planning technique to generate workflows for reconfiguring a computing infras- tructure.
Anderson, Paul, Herry, Herry
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A Hybrid Semi-Automated Workflow for Systematic and Literature Review Processes with Large Language Model Analysis

open access: yesFuture Internet
Systematic reviews (SRs) are a rigorous method for synthesizing empirical evidence to answer specific research questions. However, they are labor-intensive because of their collaborative nature, strict protocols, and typically large number of documents ...
Anjia Ye   +3 more
doaj   +1 more source

Bioinformatic Workflows for Generating Complete Plastid Genome Sequences—An Example from Cabomba (Cabombaceae) in the Context of the Phylogenomic Analysis of the Water-Lily Clade

open access: yesLife, 2018
The sequencing and comparison of plastid genomes are becoming a standard method in plant genomics, and many researchers are using this approach to infer plant phylogenetic relationships.
Michael Gruenstaeudl   +2 more
doaj   +1 more source

CrossFlow: Cross-Organizational Workflow Management for Service Outsourcing in Dynamic Virtual Enterprises [PDF]

open access: yes, 2001
In this report, we present the approach to cross-organizational workflow management of the CrossFlow project. CrossFlow is a European research project aiming at the support of cross-organizational workflows in dynamic virtual enterprises. The cooperation
Aberer, Karl   +3 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A Taxonomy of Workflow Management Systems for Grid Computing

open access: yes, 2005
With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources.
A. Geppert   +12 more
core   +4 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

ERROR HANDLING IN INTEGRATION WORKFLOWS

open access: yesНаучный вестник МГТУ ГА, 2017
Simulation experiments performed while solving multidisciplinary engineering and scientific problems require joint usage of multiple software tools.
A. M. Nazarenko, A. A. Prokhorov
doaj  

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