Results 81 to 90 of about 1,099,627 (374)
D7.1: A library of workflows and workflow nodes
, 2018 The main goal of the workpackage (WP7) is to investigate state-of-the-art IT infrastructure needed for multi-partner, multi-site, multi-component industrial biotechnology projects. The workpackage has four objectives and the deliverable is linked to the first.
Goble, Carole, Faulon, Jean-Loup
openaire +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Workflow automation in liquid chromatography mass spectrometry [PDF]
, 2019 We describe the fully automated workflow path developed for the ingest and analysis of liquid chromatography mass spectrometry (LCMS) data. With the help of this computational workflow, we were able to replace two human work days to analyze data with two
Baidoo, E +3 more
core
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Designing for Proactive Network Configuration Analysis [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 Human operators are an important aspect of any computing infrastructure; however, human errors in configuring systems pose reliability and security risks, which are increasingly serious as such systems grow more complex.
Magreth Mushi, Rudra Dutta
doaj
Digital Studies, 2011 This is the second of two issues marking the return of Digital Studies/Le champ numérique after a major change in editorial offices.
Daniel O’Donnell
doaj +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Digital Studies, 2011 This issue marks the return of Digital Studies/Le champ numérique after a major change in editorial offices.
Daniel O’Donnell
doaj +1 more source
A Generic Workflow for the Data FAIRification Process
Data Intelligence, 2020 The FAIR guiding principles aim to enhance the Findability, Accessibility, Interoperability and Reusability of digital resources such as data, for both humans and machines.
Annika Jacobsen +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source