Layer-Specific Astrocyte Morphological Responses in the CA3 Hippocampus Region During Piry Virus-Induced Encephalitis. [PDF]
ABSTRACT Astrocytes from distinct hippocampal layers exhibit region‐specific morphological traits, which may be influenced by their local microenvironment. During viral encephalitis, these cells undergo dynamic changes that can reflect layer‐specific vulnerability. In this study, we characterized whether astrocytes from different CA3 hippocampal layers
de Almeida Miranda D +10 more
europepmc +2 more sources
Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB-5'Br-PINACA, in Seized Herbal Materials. [PDF]
MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
de Godoi AB +6 more
europepmc +2 more sources
Revealing patterns of endemism in the transatlantic family Chelodesmidae (Polydesmida: Diplopoda). [PDF]
Abstract With fossil records dating back to the Silurian/Late Ordovician, millipedes stand out as one of the earliest terrestrial animal groups. Their limited vagility and high endemism make them valuable tools for formulating and testing biogeographic hypotheses, including those related to macro‐vicariance events.
Bouzan RS +4 more
europepmc +2 more sources
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
KRAS-G12C: The neglected biomarker to detect patients with MUTYH-associated polyposis. [PDF]
What's new? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Medeiros ABD +9 more
europepmc +2 more sources
AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll +19 more
wiley +1 more source
Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira +13 more
wiley +1 more source
This study introduces an in‐house spin coater for matrix‐assisted laser desorption/ionization mass spectrometry imaging, providing homogeneous matrix deposition via simultaneous spray and spin. The approach yields reproducible signals and clear metabolite distributions in complex tissues.
Lanaia Ítala Louzeiro Maciel +8 more
wiley +1 more source
Understanding Oxide Surface Stability: Theoretical Insights From Silver Chromate
Seven low‐index Miller surfaces, comprising 46 distinct terminations, were systematically investigated to determine their surface free energies as functions of the chemical potentials of the system constituents. The competition among these terminations gives rise to temperature‐dependent stability crossovers that dynamically reshape the surface energy ...
A. Facundes +3 more
wiley +1 more source
The genetics of symbiotic nitrogen fixation: comparative genomics of 14 Rhizobia Strains by resolution of protein clusters. [PDF]
The symbiotic relationship between legumes and nitrogen fixing bacteria is critical for agriculture, as it may have profound impacts on lowering costs for farmers, on land sustainability, on soil quality, and on mitigation of greenhouse gas emissions ...
BARRERO, R. +6 more
core +1 more source

