Results 31 to 40 of about 133,713 (268)

Crossflow: A Python Library for Computational Chemistry Workflows

Journal of Open Research Software
Computational chemistry research activity very frequently features workflows: a series of computational or data transformational tasks must be chained together and executed to achieve the ultimate goal.
Sam Cox, James Gebbie-Rayet, Charles Laughton   +2 more
doaj   +1 more source

GEOEssential – mainstreaming workflows from data sources to environment policy indicators with essential variables

International Journal of Digital Earth, 2020
When defining indicators on the environment, the use of existing initiatives should be a priority rather than redefining indicators each time. From an Information, Communication and Technology perspective, data interoperability and standardization are ...
Anthony Lehmann, Stefano Nativi, Paolo Mazzetti, Joan Maso, Ivette Serral, Daniel Spengler, Aidin Niamir, Ian McCallum, Pierre Lacroix, Petros Patias, Denisa Rodila, Nicolas Ray, Grégory Giuliani   +12 more
doaj   +1 more source

Business process management framework: systematic review of the trends, potentials and future

Cogent Business & Management
The dynamics of business processes necessitate effective management to achieve an optimum outcome. In this study, a systematic literature review was conducted to explore the trends, potentials and future of business process management (BPM) and modelling
Oluwatoyin Esther Akinbowale, Mulatu Fekadu Zerihun, Polly Mashigo   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A semi-automated workflow for biodiversity data retrieval, cleaning, and quality control

Biodiversity Data Journal, 2014
The compilation and cleaning of data needed for analyses and prediction of species distributions is a time consuming process requiring a solid understanding of data formats and service APIs provided by biodiversity informatics infrastructures.
Cherian Mathew, Anton Güntsch, Matthias Obst, Saverio Vicario, Robert Haines, Alan Williams, Yde de Jong, Carole Goble   +7 more
doaj   +1 more source

CONTROL-CORE: A Framework for Simulation and Design of Closed-Loop Peripheral Neuromodulation Control Systems

IEEE Access, 2022
Closed-loop Vagus Nerve Stimulation (VNS) based on physiological feedback signals is a promising approach to regulate organ functions and develop therapeutic devices.
Pradeeban Kathiravelu, Mark Arnold, Jake Fleischer, Yuyu Yao, Shubham Awasthi, Aviral Kumar Goel, Andrew Branen, Parisa Sarikhani, Gautam Kumar, Mayuresh V. Kothare, Babak Mahmoudi   +10 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Methodology for the Digitalization of the Residential Building Renovation Process through OpenBIM-Based Workflows

Applied Sciences, 2021
The European building industry is facing a strong increase in renovation processes, which are still non-cost-effective, involve unproperly coordinated stakeholders, are disturbing for the occupants, and cause important inefficiencies in the overall ...
Alberto Armijo, Peru Elguezabal, Natalia Lasarte, Matthias Weise   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source