Results 61 to 70 of about 246,522 (302)
Semantically Resolving Type Mismatches in Scientific Workflows
, 2007 Scientists are increasingly utilizing Grids to manage large data sets and execute scientific experiments on distributed resources. Scientific workflows are used as means for modeling and enacting scientific experiments.
Derouiche, Kheiredine, Nicole, Denis A
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Semantic type checking in scientific workflows
, 2009 Scientists are increasingly utilizing Grids to manage large data sets and execute scientific experiments on distributed resources [1]. Scientific workflows are used as means for modelling and enacting scientific experiments [2].
Derouiche, Kheiredine
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Sound of the Crowd: Using Social Media to develop best practices for Open Access Workflows for Academic Librarians (OAWAL) [PDF]
, 2014 For the past nine months, Graham stone and Jill emery have been promotion OAWAL: Open Access Workflows for Academic Librarians on a blog site, through facebook, through Twitter, and at in-person events in both the US and UK to raise awareness of open ...
Emery, Jill, Stone, Graham
core +3 more sources
Multilingual Workflows for Semantic Change Research
Journal of Open Humanities DataWe present a series of workflows that aim to support research in lexical semantic change, i.e. the phenomenon by which words change their meaning over time.
Paola Marongiu +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A galactic approach to neutron scattering science
Frontiers in High Performance ComputingNeutron scattering science is leading to significant advances in our understanding of materials and will be key to solving many of the challenges that society is facing today.
Gregory R. Watson +3 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source