Results 71 to 80 of about 133,713 (268)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Verification of business process workflows

open access: yesTechnological and Economic Development of Economy, 2012
Modeling of Business processes is essential in many areas. Workflows represent the Business processes. It is possible to identify potential problems while performing verification of workflows.
Henrikas Pranevičius   +1 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Workflow-Oriented Approach To Propagation Models In Heliophysics

open access: yesComputer Science, 2014
The Sun is responsible for the eruption of billions of tons of plasma andthe generation of near light-speed particles that propagate throughout the solarsystem and beyond.
Gabriele Pierantoni   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Simplifying the Development, Use and Sustainability of HPC Software

open access: yesJournal of Open Research Software, 2014
Developing software to undertake complex, compute-intensive scientific processes requires a challenging combination of both specialist domain knowledge and software development skills to convert this knowledge into efficient code.
Jeremy Cohen   +7 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Pivot subtitling workflows in the age of streaming platforms

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research
The proliferation and popularity of non-English audiovisual productions have been fostered by streaming platforms in recent years. From the point of view of translation, thelanguage diversity encountered in audiovisual content poses logistic ...
Rocío Baños   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

On the use of an IMS LD ontology for creating and executing Units of Learning: Application to the Astronomy case study

open access: yesJournal of Interactive Media in Education, 2008
This paper describes how the Astronomy case study is modelled, created and executed, using a IMS LD ontology. The ontology was aimed at overcoming the expressiveness limitations of the IMS LD XML Schema by means of a taxonomy of concepts and a set of ...
Eduardo Sánchez   +4 more
doaj   +1 more source

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