Results 71 to 80 of about 574,123 (330)
Supporting the Everyday Work of Scientists: Automating Scientific Workflows [PDF]
, 2008 This paper describes an action research project that we undertook with National Research Council Canada (NRC) scientists. Based on discussions about their \ud difficulties in using software to collect data and manage processes, we identified three ...
Mews, Keith +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Novel technical developments in mass spectrometry imaging in 2020: A mini review
Analytical Science Advances, 2021 The applicability of mass spectrometry imaging (MSI) has exponentially increased with the improvement of sample preparation, instrumentation (spatial resolution) and data analysis.
Brooke A. Dilmetz +7 more
doaj +1 more source
Constraint Expressions and Workflow Satisfiability [PDF]
, 2013 A workflow specification defines a set of steps and the order in which those steps must be executed. Security requirements and business rules may impose constraints on which users are permitted to perform those steps.
Crampton, Jason, Gutin, Gregory
core +1 more source
ROBOT: A Tool for Automating Ontology Workflows
BMC Bioinformatics, 2019 Ontologies are invaluable in the life sciences, but building and maintaining ontologies often requires a challenging number of distinct tasks such as running automated reasoners and quality control checks, extracting dependencies and application-specific
Rebecca C. Jackson +5 more
semanticscholar +1 more source
Predicting the Costs of Serverless Workflows
International Conference on Performance Engineering, 2020 Function-as-a-Service (FaaS) platforms enable users to run arbitrary functions without being concerned about operational issues, while only paying for the consumed resources.
Simon Eismann +4 more
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Preferred Workflows for Syndromic Surveillance Systems [PDF]
, 2009 Workflows are a sequence of information processing operations that people carry out to meet certain in-formational goals [1]. Using various user-centered design (UCD) techniques we uncovered the workflows that epidemiologists wished to follow when using ...
Guthrie, Glenn +2 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Bausteine ForschungsdatenmanagementThe article presents how a textual corpus can be deposited in a data repository for digital archiving purposes. It discusses which metadata standards and file formats should be used.
Francesco Gelati
doaj +1 more source