Results 81 to 90 of about 574,123 (330)

Cost-aware scheduling of deadline-constrained task workflows in public cloud environments [PDF]

, 2013
Public cloud computing infrastructure offers resources on-demand, and makes it possible to develop applications that elastically scale when demand changes.
De Turck, Filip, Handekeyn, K, Moens, Hendrik   +2 more
core  

ReStore: Reusing Results of MapReduce Jobs [PDF]

, 2012
Analyzing large scale data has emerged as an important activity for many organizations in the past few years. This large scale data analysis is facilitated by the MapReduce programming and execution model and its implementations, most notably Hadoop ...
Aboulnaga, Ashraf, Elghandour, Iman
core   +4 more sources

Active Instrument Engagement Combined with a Real-Time Database Search for Improved Performance of Sample Multiplexing Workflows.

Journal of Proteome Research, 2019
Quantitative proteomics employing isobaric reagents has been established as a powerful tool for biological discovery. Current workflows often utilize a dedicated quantitative spectrum to improve quantitative accuracy and precision.
B. Erickson, J. Mintseris, Devin K. Schweppe, José Navarrete-Perea, Alison R Erickson, David P. Nusinow, J. Paulo, S. Gygi   +7 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

SciTokens: Capability-Based Secure Access to Remote Scientific Data

, 2018
The management of security credentials (e.g., passwords, secret keys) for computational science workflows is a burden for scientists and information security officers.
Basney, Jim, Bockelman, Brian, Brown, Duncan, Gaynor, Jeff, Miller, Zach, Tannenbaum, Todd, Weitzel, Derek, Withers, Alex   +7 more
core   +1 more source

Neuroimaging study designs, computational analyses and data provenance using the LONI pipeline. [PDF]

, 2010
Modern computational neuroscience employs diverse software tools and multidisciplinary expertise to analyze heterogeneous brain data. The classical problems of gathering meaningful data, fitting specific models, and discovering appropriate analysis and ...
Chakrapani, Shruthi, Dinov, Ivo, Eggert, Paul, Gutman, Boris, Leung, Kelvin, Liu, Zhizhong, Lozev, Kamen, Magsipoc, Rico, Parker, D Stott, Petrosyan, Petros, Pierce, Jonathan, Toga, Arthur, Van Horn, John, Woods, Roger, Zamanyan, Alen   +14 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Austrian Transition to Open Access: a collaborative approach

Insights: The UKSG Journal, 2021
This article presents a collaborative project, the ‘Austrian Transition to Open Access’ (AT2OA), initially running from 2017 to 2020, which had the overarching goal of enabling the large-scale transformation of publishing outputs from closed to open ...
Rita Pinhasi, Lothar Hölbling, Brigitte Kromp   +2 more
doaj   +1 more source

GRIDCC: Real-time workflow system [PDF]

, 2007
The Grid is a concept which allows the sharing of resources between distributed communities, allowing each to progress towards potentially different goals.
Akram, A, Colling, D, Dickens, L, Guo, L, Kyberd, P, Martyniak, J, McGough, A, Powell, R S   +7 more
core  

A linked data approach to publishing complex scientific workflows [PDF]

, 2011
Past data management practices in many fields of natural science, including climate research, have focused primarily on the final research output - the research publication - with less attention paid to the chain of intermediate data results and their ...
Callaghan, Sarah, Harpham, Colin, Lawrence, Bryan, Matthews, Brian, Osborn, Timothy, Shaon, Arif, Woolf, Andrew   +6 more
core   +1 more source