Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Restructuring the English Working Class for Global Competitiveness [PDF]
, 2008 This paper considers the latest developments in an ongoing attempt to restructure the English working class. It divides this project into two distinct phases.
Nunn, A
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
How Do COVID-19 Vaccine Policies Affect the Young Working Class in the Philippines? [PDF]
Int J Environ Res Public Health, 2023 Estoce RHY, Ngan OMY, Calderon PEE.
europepmc +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Factors affecting exclusive breastfeeding practices among working-class women in Osun State, Nigeria. [PDF]
J Public Health Afr, 2023 Kayode OO, Oyedeji AS, Alabi QK.
europepmc +1 more source
Selling owner-occupation to the working-classes in 1930's Britain [PDF]
The 1930s witnessed Britain’s first major boom in working-class owner-occupation. Purchasers typically came from cramped, rented, inner-urban accommodation, and, only a few years previously, would not have considered the possibility of buying a new house.
Peter Scott
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Health Insurance Literacy Perceptions and the Needs of a Working-Class Community. [PDF]
Health Lit Res Pract, 2022 Kakar R +4 more
europepmc +1 more source
Examining How Working-Class Resident Advisors Perceive Social Class and Classism Within Residential Life [PDF]
, 2022 Genia M. Bettencourt, Brittany E. Perez
openalex +1 more source