Results 111 to 120 of about 9,821,585 (424)
FEBS Letters, EarlyView.We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring +6 more
wiley +1 more source
Upper bounds on the Natarajan dimensions of some function classes [PDF]
arXiv, 2022 The Natarajan dimension is a fundamental tool for characterizing multi-class PAC learnability, generalizing the Vapnik-Chervonenkis (VC) dimension from binary to multi-class classification problems. This work establishes upper bounds on Natarajan dimensions for certain function classes, including (i) multi-class decision tree and random forests, and ...
arxiv
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Class Vectors: Embedding representation of Document Classes [PDF]
arXiv, 2015 Distributed representations of words and paragraphs as semantic embeddings in high dimensional data are used across a number of Natural Language Understanding tasks such as retrieval, translation, and classification. In this work, we propose "Class Vectors" - a framework for learning a vector per class in the same embedding space as the word and ...
arxiv
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Parametrization of spectral surfaces of a class of periodic 5-diagonal matrices [PDF]
arXiv, 2011 The main result of this work is a parametric description of the spectral surfaces of a class of periodic 5-diagonal matrices, related to the strong moment problem. This class is a self-adjoint twin of the class of CMV matrices. Jointly they form the simplest possible classes of 5-diagonal matrices.
arxiv
THE WORKING CLASS, THE EMERGENCE OF THE CLASS CONSCIOUSNESS AND EDUCATION
Germinal : Marxismo e Educação em Debate, 2011 This article deals with the class society, the emergence of the working class, its recognition as such and the education. Starts with a brief discussion of the positivist and materialist conceptions of society and historical dialectics, following ...
Paulino José Orso
doaj
Ethnographies of the imagined, the imaginary and the critically real: Blackness, whiteness, the north of England and rugby league [PDF]
, 2010 Rugby league is part of the white, working-class (male) culture of the north of England, and is a sport that is used by its supporters to (re)produce both an imagined community of nostalgic northernness and an imaginary community of locally situated ...
Long, J, Spracklen, K, Timmins, S
core +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Feature Space Augmentation for Long-Tailed Data [PDF]
arXiv, 2020 Real-world data often follow a long-tailed distribution as the frequency of each class is typically different. For example, a dataset can have a large number of under-represented classes and a few classes with more than sufficient data. However, a model to represent the dataset is usually expected to have reasonably homogeneous performances across ...
arxiv