Results 111 to 120 of about 5,581,186 (359)

Fluid model for a network operating under a fair bandwidth-sharing policy

, 2004
We consider a model of Internet congestion control that represents the randomly varying number of flows present in a network where bandwidth is shared fairly between document transfers.
A Fair, Bandwidth-sharing Policy, F. P. Kelly, R. J. Williams   +3 more
core   +5 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Review of Reservoir Damage Mechanisms Induced by Working Fluids and the Design Principles of Reservoir Protection Fluids: From Oil–Gas Reservoirs to Geothermal Reservoirs

Energies
Various working fluids are applied during geothermal reservoir development, and geothermal reservoir damage induced by contacts between working fluids and reservoir formations are inevitable.
Ou Jiang, Ling Cao, Wenxi Zhu, Xiuhua Zheng   +3 more
doaj   +1 more source

DCHX Working Fluid Recovery System Study [PDF]

, 1982
This report addresses the DCHX working fluid recovery system study.
Collett, C., Olander, R., Oshmyansky, S., Nichols, K., Werner, D.   +4 more
openaire   +2 more sources

Program for calculating total-efficiency of specific-speed characteristics of centrifugal compressors [PDF]

, 1973
Program uses one-dimensional mean streamline analysis conducted at fixed stagnation conditions. Seven specific losses are calculated for each set of compressors geometric variables and inlet velocity diagram characteristics studied.
Galvas, M. R.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Design sensitivity analysis of using various in-tube condensation correlations for an air-cooled condenser for ORCs [PDF]

, 2015
The study is related to the evaluation of using 19 condensation heat transfer correlations in an annular finned horizontal round tube V-shaped air-cooled condenser design problem for a representative low-temperature waste heat recovery Organic Rankine ...
De Paepe, Michel, Kaya, Alihan, Lazova, Marija   +2 more
core   +1 more source

Single-atom heat machines enabled by energy quantization [PDF]

, 2018
Quantization of energy is a quintessential characteristic of quantum systems. Here we analyze its effects on the operation of Otto cycle heat machines and show that energy quantization alone may alter and increase machine performance in terms of output ...
Aspuru-Guzik, Alán, Bylinskii, Alexei, Gangloff, Dorian, Gelbwaser-Klimovsky, David, Islam, Rajibul, Vuletic, Vladan   +5 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source