Results 61 to 70 of about 3,568,194 (300)

Balancing Leisure and Work: Evidence from the Seasonal Home [PDF]

open access: yes, 2006
Seasonal homes are used during leisure time for many recreational activities, yet recent technological innovations have diminished the separation between the work place and the seasonal home.
Johnson, Kenneth M., Stewart, Susan I.
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

THE REGULATION OF DISTANT LABOR RELATIONS AT THE AIRLINES

open access: yesНаучный вестник МГТУ ГА, 2016
The article discusses how to optimize airline costs applying the Federal Law of 04.05.2013, № 60-FZ on the regulation of labor relations at the remote aviation enterprises of Russia.
K. S. Ermakov, A. V. Savyolova
doaj  

Exploring the relationship between working from home, mental and physical health and wellbeing: a systematic review

open access: yesPublic Health Research, 2023
Background Understanding the impact of working from home on health and wellbeing is of great interest to employers and employees alike, with a strong need for up-to-date guidance. The aim of this systematic review was to identify, appraise and synthesise
Blank Lindsay   +4 more
doaj   +1 more source

Headache-related clinical features in teleworkers and their association with coping strategies during the COVID-19 pandemic

open access: yesFrontiers in Public Health, 2023
ObjectivesThe objectives were (1) to describe and compare headache-related clinical features between teleworkers with migraine and those with tension-type headache (TTH) and (2) to determine the association between coping strategies and headache ...
Mariève Houle   +10 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Are We Creating Outcomes Similar to Power Sector by Proliferating Metro Rail Across Cities in India?

open access: yesVikalpa, 2021
Metro rails mitigate problems of pollution and congestion in crowded Indian cities and are therefore a priority of the government. However, they are also very expensive to build and operate, making their operations loss-making.
Kumar V. Pratap
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

A qualitative dyadic approach to explore the experiences and perceived impact of COVID-19 restrictions among adolescents and their parents

open access: yesHealth Psychology and Behavioral Medicine, 2023
Background While evidence exists for the negative and positive effects of the COVID-19 pandemic and associated lockdown on the mental health and well-being of adolescents and parents separately, the potential impact of lockdown, and the effective coping ...
Pooja Saini   +4 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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