Results 91 to 100 of about 3,276,396 (351)

Long hours and stress in the UK's IT profession: has the European Union's Working Time Directive offered relief? [PDF]

open access: yes, 2005
Only a small amount of research thus far has investigated the relationship between the working conditions of those employed in technical professions, such as Information Technology (IT), and the implications for their well being (Sonnetag et al., 1994 ...
Martin, Ian
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

"Productivity in Manufacturing and the Length of the Working Day: Evidence from the 1880 Census of Manufactures" [PDF]

open access: yes
Data from the manuscript census of manufacturing are used to estimate the effects of the length of the working day on output and wages. We find that the elasticity of output with respect to daily hours worked was positive but less than one--implying ...
Fred Bateman   +2 more
core   +3 more sources

Radiografía de la formación médico interno residente (MIR): estudio descriptivo sobre las condiciones laborales y formativas en la provincia de Valencia

open access: yesEducación Médica
Resumen: Introducción: las condiciones laborales de los médicos internos residentes (MIR) han demostrado tener un gran impacto en su salud y formación. Durante los últimos años se han publicado los primeros estudios analizando esta realidad. Sin embargo,
Lucía Escabias Criado   +4 more
doaj   +1 more source

Income, Happiness, and the Disutility of Labour [PDF]

open access: yes
We reexamine the claim that the effect of income on subjective well-being suffers from a systematic downward bias if one ignores that higher income is typically associated with more work effort.
Andreas Knabe, Steffen Rätzel
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Human Right for Fair Wage: sociological aspect

open access: yesVestnik Omskoj Ûridičeskoj Akademii, 2012
The article summarizes the results of sociological research devoted to the analysis of the fair wage problem. The authors analyze the dynamics of labor load and the level of wages in the economic market conditions taking as an example the Omsk ...
Ponomareva T. M., Kalyuga E. A.
doaj  

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