Results 91 to 100 of about 10,962,408 (345)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Effect of Self-Compassion on Job Burnout and Hours Worked in Employees’ Working from Home [PDF]

open access: yes, 2021
Working from home (WFH) has been associated with increased levels of job burnout; a psycho-physiological outcome of experiencing intense or extended periods of work-related stress.
Garip, Gulcan   +2 more
core  

Characteristics of working hours and the risk of occupational injuries among hospital employees: a case-crossover study

open access: yesScandinavian Journal of Work, Environment and Health, 2020
Objectives: We investigated the association of working hours with occupational injuries in hospital shift work. Methods: Registry data of occupational injuries of hospital employees from 11 towns and 6 hospital districts were linked to daily payroll data
M. Härmä   +5 more
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Duration of working hours: health and socio-economic Implications

open access: yesRevista Chilena de Terapia Ocupacional, 2015
A topic of relevance for occupational therapy from their bases, has been how the person distributes the time of their activities and through this reach “Occupational Balance”, recognizing its importance to the health of the human.
Christian Moretti A.
doaj   +1 more source

Gender norms, fairness and relative working hours within households

open access: yesLabour Economics, 2020
Using data in the United States, UK and Germany, we show that women whose working hours exceed those of their male partners report lower life satisfaction on average.
Sarah Flèche   +2 more
semanticscholar   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Association of long working hours with accidents and suicide mortality in Korea

open access: yesScandinavian Journal of Work, Environment and Health, 2020
Objectives: The deleterious health effects of long working hours have been previously investigated, but there is a dearth of studies on mortality resulting from accidents or suicide.
Hye-Eun Lee   +3 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Labour productivity in industries dependent on United States demand for Canadian exports

open access: yesEconomic and Social Reports
This article compares labour productivity from 1997 to 2024 between industries dependent on U.S. demand and other industries in the business sector. Labour productivity in this study is measured by real value added per hour worked.
Tahsin Medhi, Marc Frenette
doaj   +1 more source

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